ID   C9SHQ4_VERA1            Unreviewed;      1237 AA.
AC   C9SHQ4;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=C2 domain-containing protein {ECO:0000313|EMBL:EEY18477.1};
GN   ORFNames=VDBG_04586 {ECO:0000313|EMBL:EEY18477.1};
OS   Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136)
OS   (Verticillium wilt of alfalfa) (Verticillium albo-atrum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=526221 {ECO:0000313|Proteomes:UP000008698};
RN   [1] {ECO:0000313|Proteomes:UP000008698}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136
RC   {ECO:0000313|Proteomes:UP000008698};
RX   PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA   Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA   Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA   Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA   Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA   Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA   Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT   "Comparative genomics yields insights into niche adaptation of plant
RT   vascular wilt pathogens.";
RL   PLoS Pathog. 7:E1002137-E1002137(2011).
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DR   EMBL; DS985218; EEY18477.1; -; Genomic_DNA.
DR   RefSeq; XP_003004980.1; XM_003004934.1.
DR   AlphaFoldDB; C9SHQ4; -.
DR   GeneID; 9530195; -.
DR   KEGG; val:VDBG_04586; -.
DR   eggNOG; ENOG502QQWJ; Eukaryota.
DR   HOGENOM; CLU_003023_0_0_1; -.
DR   OMA; VLKSPKW; -.
DR   OrthoDB; 1984726at2759; -.
DR   Proteomes; UP000008698; Unassembled WGS sequence.
DR   CDD; cd04043; C2_Munc13_fungal; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 1.20.58.1100; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR010439; MUN_dom.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR014772; Munc13_dom-2.
DR   PANTHER; PTHR47263; ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1; 1.
DR   PANTHER; PTHR47263:SF1; C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350); 1.
DR   Pfam; PF00168; C2; 1.
DR   Pfam; PF06292; MUN; 1.
DR   SMART; SM00239; C2; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS51259; MHD2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008698}.
FT   DOMAIN          631..757
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   DOMAIN          832..954
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          1048..1169
FT                   /note="MHD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51259"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1237 AA;  141187 MW;  9A942F9F32AA7B25 CRC64;
     MSSASRNSYL HRRNDSNRGN TLKRAPSRSQ THVISHDDAY SFALRIAYLN YLLQPKTKRK
     QWVAAPKPIH KAGQRSHTAV GELIGQLSSP SGSSKITMPH GFRSSLEKRL SQVVQGSYPV
     PGYNDAAVKR SFARAYTAFT EKAFQKRADD ERKIDPYILM FYSSATKAAN ATAVQANSSE
     DHVKMLPDRH LALFVRLVSH MLRDQGVDRD RPELMKRLDS LEKKLLTHDQ NLADVNNQNE
     TKMIEVIVPL SYDVKDMPLV LLIQRVFGRT KTDVQSDIDA HRHAWTEEAA LKDIKAYQHR
     LASNAPGSLR KHDFDTDEAY EEWKKAEATH LSEILFKITT AKPELLKTSS SSLDKPLPGR
     PMSLYGEDQA YSDLSRALSN PDSATYGSDP SSMISLSSLS LEDAPGGTQT VEEPAYTFIP
     PSPRSFYKAF LQYCMTYDHL HSDPALPYAP LSPQSIDLLI ELSVFWRLPQ FTRLIVVIEV
     ASKRFLDGEI DIDQLAETLE IVKETASDHR KAPALQHYPA DQLSDFSKQV TEALRQSARD
     LYHEIVQTKL PEDAESWQFS HVIEMGKLVV QRVAKMQKRY RSMSEIKGVT PLPILVQTML
     PIFEQDAEHI IGKAIQTAQA AGCELDIDDG FDLYRELIKL RESHYKYLPG VEFHFDIEGL
     LQEFVWRWIR EAESRMEAGV INAIKLDDFR ALGDDGERLP SDAERHSASI ADLFQFFSAP
     VTQIDQLEWR NEEHHARFMT ALAHIFATGI EKYCEEVGRI FAADMERLTP QEEAMASRTT
     QERFMQYAKE AWNNKEKPEP YNFSSKAFVM LNNIEFAKQK LDKLEHTMNV DRCAEIVRVI
     DGPKQQTRRP NKYNFTVKIV EAEDLKACDP NGFSDPYVVL VDERQKRLHK TRVVRKSLNP
     RWDESRDITV TAPITIIATV WDDDMFGDHD FVGRTSFKLD PVHFSDYIPR EIWLDLDTQG
     RILVKISMEG ERDDIEFQFG KAFRDLKRTE QIMVRKITEK LRDQINTSLS HETLRRLLGG
     AGIGAQVTSL WKKRTSVMPT VPSKAVIDES LDPLMDYFHA NFTIMNQTLT NDTMRSVMLR
     LWKEVLLAVE ALLVPPLSDK PSEQRPLSRF EVDIVYGWLR QLLSFFNAKD EEGNELGVPE
     NDLRSPKWHE LASLNFFYFE DTATLVRESE RMAASNAQKA ANYLKERSRQ KERQSARTAA
     MMIVNNSVSQ GWALAGPAAP RTRGTICLGG EHRRASE
//