ID C9XXT6_CROTZ Unreviewed; 414 AA.
AC C9XXT6;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Acriflavine resistance protein A {ECO:0000313|EMBL:CBA28744.1};
GN Name=acrA {ECO:0000313|EMBL:CBA28744.1};
GN OrderedLocusNames=Ctu_10700 {ECO:0000313|EMBL:CBA28744.1};
OS Cronobacter turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827 / z3032).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Cronobacter.
OX NCBI_TaxID=693216 {ECO:0000313|EMBL:CBA28744.1, ECO:0000313|Proteomes:UP000002069};
RN [1] {ECO:0000313|Proteomes:UP000002069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18703 / CCUG 55852 / LMG 23827 / z3032
RC {ECO:0000313|Proteomes:UP000002069};
RX PubMed=21037008; DOI=10.1128/JB.01162-10;
RA Stephan R., Lehner A., Tischler P., Rattei T.;
RT "Complete genome sequence of Cronobacter turicensis LMG 23827, a food-borne
RT pathogen causing deaths in neonates.";
RL J. Bacteriol. 193:309-310(2011).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; FN543093; CBA28744.1; -; Genomic_DNA.
DR AlphaFoldDB; C9XXT6; -.
DR KEGG; ctu:CTU_10700; -.
DR PATRIC; fig|693216.3.peg.1042; -.
DR HOGENOM; CLU_018816_2_1_6; -.
DR Proteomes; UP000002069; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 51..373
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 77..306
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 385..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 414 AA; 44189 MW; 2B04CB63119FDE1B CRC64;
MGHFLESNTR GLDMNKNRGF TPLAVVLMLS GSFALTGCDG EQAQQQAPQA PEVGVVTLKS
EPLQITTELP GRTLAYRVAE VRPQVSGIIL KRNFEEGSEI KAGVSLYQID PAPYQASYES
AKGDLAKAQA SANIAQVTLS RYQKLLGTQY ISKQDYDNAQ AEAQQANAAV VAAKAAVETA
RINLAYTKVT SPISGRIGKS NVTEGALVQN GQTTALAVVQ QLDPIYVDVT QSSNDFLRLK
QELASGQLKQ ENGKAKVTLS TADGLKYPQD GTLEFSDVTV DQTTGSITLR AIFPNPDHTL
LPGMFVRARL EEGVNPTAIL VPQQGVTRTP RGDATVMVVG EGDKVEVRPV TVGQAMGDKW
VVTDGVKAGD RVIISGLQKV RPGAQVKAQE VTDNQQQQKQ SGAAGQTQSQ QPQS
//
