ID C9Z746_STRSW Unreviewed; 774 AA.
AC C9Z746;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Putative integral membrane protein {ECO:0000313|EMBL:CBG71440.1};
GN OrderedLocusNames=SCAB_43761 {ECO:0000313|EMBL:CBG71440.1};
OS Streptomyces scabiei (strain 87.22).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=680198 {ECO:0000313|EMBL:CBG71440.1, ECO:0000313|Proteomes:UP000001444};
RN [1] {ECO:0000313|EMBL:CBG71440.1, ECO:0000313|Proteomes:UP000001444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=87.22 {ECO:0000313|EMBL:CBG71440.1,
RC ECO:0000313|Proteomes:UP000001444};
RX PubMed=20064060; DOI=10.1094/MPMI-23-2-0161;
RA Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J.,
RA Loria R.;
RT "Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic
RT cluster that contributes to plant-microbe interactions.";
RL Mol. Plant Microbe Interact. 23:161-175(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN554889; CBG71440.1; -; Genomic_DNA.
DR AlphaFoldDB; C9Z746; -.
DR STRING; 680198.SCAB_43761; -.
DR KEGG; scb:SCAB_43761; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_1_1_11; -.
DR Proteomes; UP000001444; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001444};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 387..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..629
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 656..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..709
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..388
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 483..717
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 730..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 774 AA; 79163 MW; 217E3A7339AB6D0A CRC64;
MLSKALLRLG AGAARHPWRV IAAWLVATTL AVLAAVAFGG RTADSMTAPG LDSQKAAELI
GRARTGQEGM TAQVVVTPRD GAATFFDRGG ARTALTRLRA EVERLPHVLG TSDPAGALDA
RGDAAVRGGL VSADGRIAVV RVQYPDQSRL SAEDLDALVG LGDRLRAELP LRIEMGGNLF
YAFSDPDGGA SELIGLLAAA AILFLAFGSL VAAALPIGMA VFGLTVGVAT MTLLAGVTDV
PTFAPVLGSM VGLGVGIDYA LFVLARHREY LAGGVDPRTA AGRAVATAGR PVVFAGGTVV
VSILGLAVAN VPFMTVGGVA VSIVVLIMVL ASVTLLPAFL GAAGPRLARA GRIGRALRAG
RRRDVAAGAA PAVGWRRWIG HVGRHPVPYA VGAAGLLLTA TLPVLGLRVG LPDDGSLPPG
RTERRAYDLV AEGFGPGTNG PLVVAADPAG DPGVLDRLVG AVAADPGIAS VAPAHVDRAT
GIATLVVFPA TGPQDEATAD TIARLRTDVL PTAIGHGPAR AHVGGAAASL SDVGQRTSER
LPAFVAAVLA MSFLLLMLVF RSVLVPLKAV LLNLLSIGAA YGVMVAVFQW GWGGALIGLE
ATVPIVSFIP MFLFAILFGL SMDYEVFLLS RVREEYLRTG DNGTAIVEGV SRTARIITSA
ALIMVAVFLS FAVADDPSTK MFGLGLATAI LIDATVVRMV LVPATMTLLG RANWWLPKWL
DRMLPRGPVG TADTGGTDAE ATGEAGQGRG GTADSGIDGE AAGGRTRRGP AGPR
//
