ID C9ZCE4_STRSW Unreviewed; 731 AA.
AC C9ZCE4;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Putative integral membrane protein {ECO:0000313|EMBL:CBG73344.1};
GN OrderedLocusNames=SCAB_63341 {ECO:0000313|EMBL:CBG73344.1};
OS Streptomyces scabiei (strain 87.22).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=680198 {ECO:0000313|EMBL:CBG73344.1, ECO:0000313|Proteomes:UP000001444};
RN [1] {ECO:0000313|EMBL:CBG73344.1, ECO:0000313|Proteomes:UP000001444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=87.22 {ECO:0000313|EMBL:CBG73344.1,
RC ECO:0000313|Proteomes:UP000001444};
RX PubMed=20064060; DOI=10.1094/MPMI-23-2-0161;
RA Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J.,
RA Loria R.;
RT "Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic
RT cluster that contributes to plant-microbe interactions.";
RL Mol. Plant Microbe Interact. 23:161-175(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN554889; CBG73344.1; -; Genomic_DNA.
DR RefSeq; WP_013003904.1; NC_013929.1.
DR AlphaFoldDB; C9ZCE4; -.
DR STRING; 680198.SCAB_63341; -.
DR GeneID; 24306920; -.
DR KEGG; scb:SCAB_63341; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_1_11; -.
DR Proteomes; UP000001444; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001444};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 521..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 551..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..692
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..375
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 480..700
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 712..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..731
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 76672 MW; 215967CB5286B237 CRC64;
MFSALGSALH RRRIVLLLLT LLVTALATVY GGTVEEKLSN GLSDYDDPGG GNVAAREIIE
RATGIDPQQG HLLLVRTDER LAEDTAPPKA VTAAAELLRS RPEVEQVLDY TSPDGAALIS
RDGRSTVVVG ATGSMTDQES ARAVEALQKA IDDDPTLRDR TWLGGATPGH VQVAEVSSTD
LGQAELLATP VILVVLFVVF RGLVAALVPL LGGIVSLLLT MAGLRVATEF MNVSTGATSL
AFALGLGLSI DFGLLLVSRY REELAEHGPG AEAVRRTVAT AGRTVLFSAL TVAAALAALI
AFPQPYLRSM GLAGVITVVS AALFALLGLP PLLALLGKRI NSLAPRRWQR TAGAARATEG
RWYRVAQAVM RRPAVFALAA TAVLLLIASP LLGVRFTGVD PTLLPEETSA GKVAAVLDED
YDARATSPLQ IVLETDGAPD TARLADYTER IGAVPGVRSV GTPVELGDRY WEIDAVLAED
PLTDSSKDAV GAVQDLAAPY PARYTGRTAD FLAQRQSIAD ALPLAGGILV VVTLLLLFAF
SGSVVLPLKA LLMNLLSTGA AFGFLVWVFQ DGNLGFAPQT GLEATTPVLV FALAFGLSTD
YNVFLLSRIK EARAQGLDNR EAVAQGLSRT GGIVTSAAVL FCIPVGALAM SRLVFIQELG
LGAAFAVLID ATVVRAFLVP SLMALLGAAN WWAPAPLRAL HRALRLDRME HTEAPEPAPA
PAPDRTSAPV G
//
