ID C9ZED1_STRSW Unreviewed; 380 AA.
AC C9ZED1;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Putative polyketide KS component {ECO:0000313|EMBL:CBG74922.1};
GN OrderedLocusNames=SCAB_79621 {ECO:0000313|EMBL:CBG74922.1};
OS Streptomyces scabiei (strain 87.22).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=680198 {ECO:0000313|EMBL:CBG74922.1, ECO:0000313|Proteomes:UP000001444};
RN [1] {ECO:0000313|EMBL:CBG74922.1, ECO:0000313|Proteomes:UP000001444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=87.22 {ECO:0000313|EMBL:CBG74922.1,
RC ECO:0000313|Proteomes:UP000001444};
RX PubMed=20064060; DOI=10.1094/MPMI-23-2-0161;
RA Bignell D.R., Seipke R.F., Huguet-Tapia J.C., Chambers A.H., Parry R.J.,
RA Loria R.;
RT "Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic
RT cluster that contributes to plant-microbe interactions.";
RL Mol. Plant Microbe Interact. 23:161-175(2010).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
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DR EMBL; FN554889; CBG74922.1; -; Genomic_DNA.
DR AlphaFoldDB; C9ZED1; -.
DR STRING; 680198.SCAB_79621; -.
DR KEGG; scb:SCAB_79621; -.
DR eggNOG; COG0304; Bacteria.
DR HOGENOM; CLU_000022_69_0_11; -.
DR Proteomes; UP000001444; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF336; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001444};
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..374
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 380 AA; 38622 MW; 52842B3F4C4CBB3D CRC64;
MSTGSQVWVT GRAWSTALGS DVDTVWEALL AGASGITEVS SPVPLRGTLA ATVPDLDSDL
PAWDRQQRLT RATLSKALRD AGIDPGDPRV LPVLGTSYGP HLEMPDTGSL SHWSVTAARD
AGCVVEPVTV TTACSAGSDA VLAGLALLEE GVADVCVCGG ADVLTLGKRL GHSHLGTMSP
DGLRAFDTAR NGTVLGEGAA FLVLERAEHA RARGARPYGV VAGAGSSNDA ASAVAPDPSG
ANVVLAVERA LRDADITPED VTVVNAHGSG TPVNDDVEAR AYARLFAGVP RPPVAFATKG
AFGHTLGATG AIEAVALLQA LATGTVPPVP SLRDPLSRLG LPIPMERPMK AEPGRGISVT
LGFGGFNTCL VLQGPESVAT
//
