ID   C9ZXP3_TRYB9            Unreviewed;       409 AA.
AC   C9ZXP3;
DT   24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   24-NOV-2009, sequence version 1.
DT   13-SEP-2023, entry version 36.
DE   RecName: Full=Divalent cation transporter {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TbgDal_IX2630 {ECO:0000313|EMBL:CBH14188.1};
OS   Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=679716 {ECO:0000313|EMBL:CBH14188.1, ECO:0000313|Proteomes:UP000002316};
RN   [1] {ECO:0000313|Proteomes:UP000002316}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MHOM/CI/86/DAL972 {ECO:0000313|Proteomes:UP000002316};
RX   PubMed=20404998; DOI=10.1371/journal.pntd.0000658;
RA   Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A.,
RA   Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W.,
RA   Barry J.D., Berriman M., Hertz-Fowler C.;
RT   "The genome sequence of Trypanosoma brucei gambiense, causative agent of
RT   chronic human african trypanosomiasis.";
RL   PLoS Negl. Trop. Dis. 4:E658-E658(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FN554972; CBH14188.1; -; Genomic_DNA.
DR   RefSeq; XP_011776458.1; XM_011778156.1.
DR   AlphaFoldDB; C9ZXP3; -.
DR   GeneID; 23860258; -.
DR   KEGG; tbg:TbgDal_IX2630; -.
DR   VEuPathDB; TriTrypDB:Tbg972.9.2630; -.
DR   OrthoDB; 150613at2759; -.
DR   Proteomes; UP000002316; Chromosome 9.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd12829; Alr1p-like; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   InterPro; IPR044089; Alr1-like.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR   PANTHER; PTHR21535:SF51; MANGANESE RESISTANCE PROTEIN MNR2; 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        338..358
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        370..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   409 AA;  45748 MW;  F4CC0EEBD895D45D CRC64;
     MTVSEFGRSR VLYRRNGVSD VIEVGNTTEL NDVIALLRSF SGVPKSYTTL VTPSLAELCE
     DAVGVERLWT SSAERTEPKD FAWLEVETES DEVMRQVLSA FPIHSKTSEL VRSSENRVEV
     VEIFPSCGYV WVSIAAKGAA SESSVPEDDE PVVVSLIAYE QFLITMHRKP LSGFEDMKAH
     MEMLVKSPAS YGAPVPTAVC SLISGFVKEY QKELLSLLVD VDNVNELVLE IQPSECDQLD
     LLRRIDDLRH SLSRVQASYF AKERVLQRLL LPVVKRTFIS SAVGVAARYQ RMLSGLILSI
     ERLRKGRDVL NMSSMGLVSG VSMRLLQRCY WMDYLNNVMT MMTLVSMPIS IIPGLFTMNV
     RVPFEDSESF VPFYVIVAVT AGIFFLGMSY PVYLYLTFKS PGALVPTSH
//