ID CCD42_ORYSJ Reviewed; 383 AA.
AC Q4KYM5; A0A0P0XHR2; Q5SD44; Q5SD46; Q6DMP1; Q6DMP6; Q6DMP7; Q6DMQ0; Q6DMQ7;
AC Q6ZB91;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 2.
DT 27-MAR-2024, entry version 98.
DE RecName: Full=Cyclin-D4-2;
DE AltName: Full=G1/S-specific cyclin-D4-2;
DE Short=CycD4;2;
GN Name=CYCD4-2; OrderedLocusNames=Os08g0479300, LOC_Os08g37390;
GN ORFNames=OJ1113_A10.14, OsJ_026575;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP PARTIAL NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Taipei 309;
RA Elumalai S., Qu R., Sivamani T., Davis S.J., Au M.R., Gossett N.J.,
RA Childress R.H., Navolio L.E., Hicks B.N.;
RT "Partial putative D type cyclin in rice.";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16435118; DOI=10.1007/s00438-005-0093-5;
RA La H., Li J., Ji Z., Cheng Y., Li X., Jiang S., Venkatesh P.N.,
RA Ramachandran S.;
RT "Genome-wide analysis of cyclin family in rice (Oryza sativa L.).";
RL Mol. Genet. Genomics 275:374-386(2006).
CC -!- SIMILARITY: Belongs to the cyclin family. Cyclin D subfamily.
CC {ECO:0000305}.
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DR EMBL; AP004643; BAD09749.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF23968.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT05907.1; -; Genomic_DNA.
DR EMBL; CM000145; EAZ43092.1; -; Genomic_DNA.
DR EMBL; AK070025; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AY659999; AAV65960.1; -; Genomic_DNA.
DR EMBL; AY660022; AAV66348.1; -; Genomic_DNA.
DR EMBL; AY660030; AAT72758.1; -; Genomic_DNA.
DR EMBL; AY660533; AAT72760.1; -; Genomic_DNA.
DR EMBL; AY660537; AAT72761.1; -; Genomic_DNA.
DR EMBL; AY660569; AAT72763.1; -; Genomic_DNA.
DR EMBL; AY660570; AAT72762.1; -; Genomic_DNA.
DR EMBL; AY660573; AAV69066.1; -; Genomic_DNA.
DR EMBL; AY660575; AAT72759.1; -; Genomic_DNA.
DR RefSeq; XP_015648876.1; XM_015793390.1.
DR AlphaFoldDB; Q4KYM5; -.
DR SMR; Q4KYM5; -.
DR STRING; 39947.Q4KYM5; -.
DR PaxDb; 39947-Q4KYM5; -.
DR EnsemblPlants; Os08t0479300-01; Os08t0479300-01; Os08g0479300.
DR GeneID; 4345844; -.
DR Gramene; Os08t0479300-01; Os08t0479300-01; Os08g0479300.
DR KEGG; osa:4345844; -.
DR eggNOG; KOG0656; Eukaryota.
DR HOGENOM; CLU_048040_1_1_1; -.
DR InParanoid; Q4KYM5; -.
DR OMA; RSEAIGW; -.
DR OrthoDB; 3789612at2759; -.
DR PlantReactome; R-OSA-9640760; G1 phase.
DR PlantReactome; R-OSA-9640887; G1/S transition.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q4KYM5; OS.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0044772; P:mitotic cell cycle phase transition; IBA:GO_Central.
DR CDD; cd20543; CYCLIN_AtCycD-like_rpt1; 1.
DR CDD; cd20544; CYCLIN_AtCycD-like_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR039361; Cyclin.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR004367; Cyclin_C-dom.
DR InterPro; IPR006671; Cyclin_N.
DR InterPro; IPR048258; Cyclins_cyclin-box.
DR PANTHER; PTHR10177:SF564; CYCLIN-D4-2; 1.
DR PANTHER; PTHR10177; CYCLINS; 1.
DR Pfam; PF02984; Cyclin_C; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 1.
DR SMART; SM01332; Cyclin_C; 1.
DR SUPFAM; SSF47954; Cyclin-like; 1.
DR PROSITE; PS00292; CYCLINS; 1.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Cyclin; Reference proteome.
FT CHAIN 1..383
FT /note="Cyclin-D4-2"
FT /id="PRO_0000287032"
FT REGION 51..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..334
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 35..37
FT /note="VGE -> RWG (in Ref. 6; AAT72763)"
FT /evidence="ECO:0000305"
FT CONFLICT 35
FT /note="V -> W (in Ref. 6; AAT72761)"
FT /evidence="ECO:0000305"
FT CONFLICT 37
FT /note="E -> G (in Ref. 6; AAT72762/AAV66348)"
FT /evidence="ECO:0000305"
FT CONFLICT 224
FT /note="K -> E (in Ref. 5; AK070025)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 383 AA; 41660 MW; 5F3FA684C85F16D5 CRC64;
MAPSSSSCHD AAASMLLCAE DNSSILWLED EEGEVGERRS GGCRSMVGDL AAGGGGGSGG
GGVEEEEDMF PRQSEECVAS LVEREQAHMP RADYGERLRG GGGDVDLRVR SEAIGWIWEV
YTYYNFSSVT AYLAVNYLDR FLSQYELPEG RDWMTQLLSV ACLSIAAKME ETVVPQCLDL
QIGEPRFLFE VETIHRMELL VLTNLNWRMQ AVTPFSYIDY FLRKLNSGNA APRSWLLRSS
ELILRIAAGT GFLEFRPSEI AAAVAATVAG EATGVVEEDI AEAFTHVDKG RVLQCQEAIQ
DHHYSMATIN TVQPKPASTR RGSASASSSS VPESPVAVLD AGCLSYKSDD TDAATIASHG
GGRRKSCFDS SPVTSKKRRK LSR
//
