ID CDC63_SULTO Reviewed; 386 AA.
AC Q96YK7;
DT 19-SEP-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 27-MAR-2024, entry version 119.
DE RecName: Full=ORC1-type DNA replication protein 3 {ECO:0000255|HAMAP-Rule:MF_01407};
GN Name=cdc6-3; OrderedLocusNames=STK_21650;
OS Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
OS (Sulfolobus tokodaii).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfurisphaera.
OX NCBI_TaxID=273063;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX PubMed=11572479; DOI=10.1093/dnares/8.4.123;
RA Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M.,
RA Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y.,
RA Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T.,
RA Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K.,
RA Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.;
RT "Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon,
RT Sulfolobus tokodaii strain7.";
RL DNA Res. 8:123-140(2001).
CC -!- FUNCTION: Involved in regulation of DNA replication.
CC {ECO:0000255|HAMAP-Rule:MF_01407}.
CC -!- SIMILARITY: Belongs to the CDC6/cdc18 family. {ECO:0000255|HAMAP-
CC Rule:MF_01407}.
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DR EMBL; BA000023; BAB67270.1; -; Genomic_DNA.
DR RefSeq; WP_010980245.1; NC_003106.2.
DR AlphaFoldDB; Q96YK7; -.
DR SMR; Q96YK7; -.
DR STRING; 273063.STK_21650; -.
DR GeneID; 1460238; -.
DR KEGG; sto:STK_21650; -.
DR PATRIC; fig|273063.9.peg.2458; -.
DR eggNOG; arCOG00467; Archaea.
DR OrthoDB; 195574at2157; -.
DR Proteomes; UP000001015; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd08768; Cdc6_C; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01407; ORC1_type_DNA_replic_protein; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR015163; Cdc6_C.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF09079; Cdc6_C; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01074; Cdc6_C; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT CHAIN 1..386
FT /note="ORC1-type DNA replication protein 3"
FT /id="PRO_0000151023"
FT BINDING 65..69
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
FT BINDING 206
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01407"
SQ SEQUENCE 386 AA; 44022 MW; 6DB44097EA1EE44E CRC64;
MSIRDTLKGG KGEVIKDPRV FIDPLTVFKD IPFREDILKE VAVAVRYFVK SDVKFSTLFL
GLTGTGKTFV ARYMLNEIEE VKQEDSDYSK VKQAYVNCRE VGGTPQAVLS ALTERLTTDE
VPKHGINLGE YIEKIKEELN GKKALVYLDE VDTLIKRRGG DIVLYQLLRA DADISVIMIS
NDINIRDYME PRVLSSLGPT VFFKPYDAEQ LKHILSIYAE YGLYRGTYDD NILSYIAAIS
AKEHGDARKA VNLLFRAAQL ASGEGFIRKD HVDRAIIEYE QERLIEAIKA LPFHYKLALM
ATMDAEDVVT AHKIYSDLCN QYKQKPLSYR RFSDIISELD MFGIIKVKII NKGRAGGIRK
YIEITDKDKI RKALEDTMNL GFEEQW
//
