ID   CNDG2_XENLA             Reviewed;        1156 AA.
AC   Q2TAW0; Q4QR24; Q68F16;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-APR-2013, entry version 38.
DE   RecName: Full=Condensin-2 complex subunit G2;
DE   AltName: Full=Chromosome-associated protein G2;
DE   AltName: Full=Non-SMC condensin II complex subunit G2;
DE   AltName: Full=XCAP-G2;
GN   Name=ncapg2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION IN CONDENSIN-2 COMPLEX WITH SMC2; SMC4; NCAPG2; NCAPH2
RP   AND NCAPD3, AND FUNCTION OF THE COMPLEX.
RX   PubMed=14532007; DOI=10.1016/S0092-8674(03)00724-4;
RA   Ono T., Losada A., Hirano M., Myers M.P., Neuwald A.F., Hirano T.;
RT   "Differential contributions of condensin I and condensin II to mitotic
RT   chromosome architecture in vertebrate cells.";
RL   Cell 115:109-121(2003).
CC   -!- FUNCTION: Regulatory subunit of the condensin-2 complex, a complex
CC       which establishes mitotic chromosome architecture and is involved
CC       in physical rigidity of the chromatid axis (By similarity).
CC   -!- SUBUNIT: Component of the condensin-2 complex, which contains the
CC       smc2 and smc4 heterodimer, and three non SMC subunits that
CC       probably regulate the complex: ncaph2, ncapd3 and ncapg2
CC       (Probable).
CC   -!- SUBCELLULAR LOCATION: Nucleus (By similarity).
CC   -!- SIMILARITY: Contains 1 HEAT repeat.
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DR   EMBL; BC080030; AAH80030.1; -; mRNA.
DR   EMBL; BC097657; AAH97657.1; -; mRNA.
DR   EMBL; BC110705; AAI10706.1; -; mRNA.
DR   RefSeq; NP_001086462.1; NM_001092993.1.
DR   UniGene; Xl.13964; -.
DR   DIP; DIP-48590N; -.
DR   GeneID; 446284; -.
DR   KEGG; xla:446284; -.
DR   CTD; 54892; -.
DR   Xenbase; XB-GENE-1002747; ncapg2.
DR   HOVERGEN; HBG074124; -.
DR   KO; K11492; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   GO; GO:0007067; P:mitosis; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024741; Condensin2_G2.
DR   Pfam; PF12422; Condensin2nSMC; 2.
DR   SUPFAM; SSF48371; ARM-type_fold; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; FALSE_NEG.
PE   1: Evidence at protein level;
KW   Cell cycle; Cell division; DNA condensation; Mitosis; Nucleus.
FT   CHAIN         1   1156       Condensin-2 complex subunit G2.
FT                                /FTId=PRO_0000255944.
FT   REPEAT      460    498       HEAT.
FT   CONFLICT    131    131       H -> Y (in Ref. 1; AAH80030).
FT   CONFLICT    193    193       T -> A (in Ref. 1; AAH80030).
SQ   SEQUENCE   1156 AA;  131374 MW;  15EA008EEDD09F08 CRC64;
     MSKREAFLQA TAKDSVEDFL SFIQLHKDVS DPFDLNELLQ ELSRKQKEEL WEKLKTLLTE
     ALVANPVERW QNIDDDSDDD MEVESSSDVK QTMCVIHGVT IAAAASLCVI DEDVCYETLL
     ECAAILSGIV HALPKSESHI TLAIRHLCEA WWEKGLQGKE EFGKTAFLLL LAKSLEVKCV
     VADIGRLWHL HQTLLSFDFN SEESHNVKDL LLQCFLSINH IKKEEGRRFL SFLFSWDVNF
     IKMIHGTIKN QLQCLPKSLM THIADIYFRA WKKASGDVLQ TIEQSCIQDF MHHGVHLPRN
     SPLHPKVREV LSYFHQQKLR QGVEEMLYNL YQPIIWRGLK ARNSEVRSNA ALLFVEAFPI
     RDPNLNHEDM DNEIQKQFEE LFNLLEDPQP LVRSTGVLGV CKITAKYWEM IPPAILTDLL
     RKILGDLAAD VSSADVRCSV FKCLPILLDN KLSHPLLENM LPALKFCLHD NSEKVRVAFV
     DMLLKIKAVR AAKFWKICPM EQILARLEVD SRPVSRRIVN LLFNSFFPVN QQEEVWCERC
     VALIQMNPAA ARKFYQYAYE HTAPTNIAKL MLTIRRCLNA CINRTVPNED TEDEDDDEGD
     GEGIVRGDSE KENKSVLENV LSTEDSASMA SLLEIVVVLW RSIRKALDQN EEAKTYTISK
     FASVLPEYFK AFKEERCTVP LIILASFMPP AAVPTFSCSV LSKLRHLDSG ADEQKYSTLI
     DCLCRWGQVG HVLELASEWL SESYPEKRGR KDSNRQVRIQ DTMESKPALA LDYIEYIMTH
     TMNRDCLLSL QTKKLNQLLK VLGLVKEVLF CYIKPSEAVT HNVNQDTALR AFSLYCRLSI
     HLQHKFSSEG RTYLSVLEDT GGWIESQVLP TLESNQDISE EPRNMCHQIL KAYLTVCKDV
     LMVGLADSEF QAQLLQITLS VIQTEKCHNC LPMLFYVLKE ITELCLAHKM SDASVECDEM
     LDAIQKAFHK SLETVARRLR KQREEALQLL QTIQLPLGEF VHTVQCWHTA SKVLHRGTLS
     TLLAAVVVEI SHSLRKITDL SELTPPSSIS DLPPLSKCIM TIIVKSPSAV SSFLDELTEC
     ITLEEVEGIL SLTAALYVAV VSSKRKQIPP AVKNTASAIY RKLKNFCEVT MDDAGSIERA
     VYESSMRILN EMLHPS
//