ID D0A7J9_TRYB9 Unreviewed; 544 AA.
AC D0A7J9;
DT 24-NOV-2009, integrated into UniProtKB/TrEMBL.
DT 24-NOV-2009, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Leucine-rich repeat protein (LRRP) {ECO:0008006|Google:ProtNLM};
GN ORFNames=TbgDal_XI7690 {ECO:0000313|EMBL:CBH17650.1};
OS Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=679716 {ECO:0000313|EMBL:CBH17650.1, ECO:0000313|Proteomes:UP000002316};
RN [1] {ECO:0000313|Proteomes:UP000002316}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/CI/86/DAL972 {ECO:0000313|Proteomes:UP000002316};
RX PubMed=20404998; DOI=10.1371/journal.pntd.0000658;
RA Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A.,
RA Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W.,
RA Barry J.D., Berriman M., Hertz-Fowler C.;
RT "The genome sequence of Trypanosoma brucei gambiense, causative agent of
RT chronic human african trypanosomiasis.";
RL PLoS Negl. Trop. Dis. 4:E658-E658(2010).
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DR EMBL; FN554974; CBH17650.1; -; Genomic_DNA.
DR RefSeq; XP_011779914.1; XM_011781612.1.
DR AlphaFoldDB; D0A7J9; -.
DR GeneID; 23867794; -.
DR KEGG; tbg:TbgDal_XI7690; -.
DR VEuPathDB; TriTrypDB:Tbg972.11.7690; -.
DR OrthoDB; 126839at2759; -.
DR Proteomes; UP000002316; Chromosome 11.
DR GO; GO:0005929; C:cilium; IEA:UniProt.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR18849:SF0; CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED; 1.
DR PANTHER; PTHR18849; LEUCINE RICH REPEAT PROTEIN; 1.
DR Pfam; PF12799; LRR_4; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 204..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 358..385
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 227..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..258
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 58710 MW; 670FFDF5A5B6B857 CRC64;
MKIDLSHRNI NKFDSSAFCS EDEKEILCSI EQLDLSHNNI SSLGSLHSLT ALTVLDVSHN
NLMSLRPLPT TLRQLAASFN ALRDLDGVAQ LPRLEVLVVT NNHVTSLLGL PPTLLTLDVS
ANMLSSFTGV EKCTNLREVQ ARHNVVRSAE GLVSLRGLRS LKTLALAGNP VASSRRHFLA
VQAVLPPSIA TIDFPSTAAV LVSTSHSDTP PLRDATHLPG HSTDAHDATA FKSSSSSTAE
TEVSEEGNRE KRVSSHKEEG WECSKEMLAY TMRTQSALEE VNNLGCRTAY TSVDVSQDTS
DGRTSPQPIH SDPTQSVAEC YEEDPMEYVL RHLQSELRCC QMTCESYEKA NGELYRRVQA
LEHTNGKLAD ENAALLERLQ KMQRTLDCVL SPPPGRNNFA GTFDGTRGVG EHSTVPSLSS
HEHTSGIFSE RAGATRDAVA HAKLNGSPSR SGKTAVGVAS TKKAETRQGA RSLAKLLMAV
VPQQKAGTSP SQHCSVVDRS TNNNKSINNS SHCYSSTQSP FASDASCLTK SMNVSASGDA
DFEN
//
