ID D0FZY1_PROMI Unreviewed; 883 AA.
AC D0FZY1;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=AAA family ATPase {ECO:0000313|EMBL:QKV33832.1};
GN ORFNames=GJR66_16685 {ECO:0000313|EMBL:QKV33832.1};
OS Proteus mirabilis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Proteus.
OX NCBI_TaxID=584 {ECO:0000313|EMBL:BAI48472.1};
RN [1] {ECO:0000313|EMBL:BAI48472.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TUM4660 {ECO:0000313|EMBL:BAI48472.1};
RX PubMed=20566768; DOI=10.1128/AAC.00111-10;
RA Harada S., Ishii Y., Saga T., Tateda K., Yamaguchi K.;
RT "Chromosomally encoded blaCMY-2 located on a novel SXT/R391-related
RT integrating conjugative element in a Proteus mirabilis clinical isolate.";
RL Antimicrob. Agents Chemother. 54:3545-3550(2010).
RN [2] {ECO:0000313|EMBL:ALN43760.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PM14C28 {ECO:0000313|EMBL:ALN43760.1};
RX PubMed=26824957; DOI=10.1128/AAC.02852-15;
RA Lei C.W., Zhang A.Y., Wang H.N., Liu B.H., Yang L.Q., Yang Y.Q.;
RT "Characterization of SXT/R391 Integrative and Conjugative Elements in
RT Proteus mirabilis Isolates from Food-Producing Animals in China.";
RL Antimicrob. Agents Chemother. 60:1935-1938(2016).
RN [3] {ECO:0000313|EMBL:ASF20386.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JN39 {ECO:0000313|EMBL:ASF20386.1};
RX PubMed=28602701; DOI=10.1016/j.ijantimicag.2017.01.045;
RA Bie L., Wu H., Wang X.H., Wang M., Xu H.;
RT "Identification and characterization of new members of the SXT/R391 family
RT of integrative and conjugative elements (ICEs) in Proteus mirabilis.";
RL Int. J. Antimicrob. Agents 50:242-246(2017).
RN [4] {ECO:0000313|EMBL:QKV33832.1, ECO:0000313|Proteomes:UP000509662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HN2p {ECO:0000313|EMBL:QKV33832.1,
RC ECO:0000313|Proteomes:UP000509662};
RA Wang X., Wang H.;
RT "Proteus mirabilis strain HN2p, complete sequence.";
RL Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KT894734; ALN43760.1; -; Genomic_DNA.
DR EMBL; KY437729; ASF20386.1; -; Genomic_DNA.
DR EMBL; AB525688; BAI48472.1; -; Genomic_DNA.
DR EMBL; CP046048; QKV33832.1; -; Genomic_DNA.
DR RefSeq; WP_004249347.1; NZ_WEKK01000002.1.
DR AlphaFoldDB; D0FZY1; -.
DR PATRIC; fig|584.120.peg.3001; -.
DR Proteomes; UP000509662; Chromosome hn2p.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32182:SF22; ATP-DEPENDENT ENDONUCLEASE, OLD FAMILY-RELATED; 1.
DR PANTHER; PTHR32182; DNA REPLICATION AND REPAIR PROTEIN RECF; 1.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 268..533
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
SQ SEQUENCE 883 AA; 98748 MW; 7D43B75391790D1D CRC64;
MFTKARFFKC ALQVNPAGYI KYRGQQQTIT EDEYNQNLLA ASLEAGIEVI GLADHGSVDG
VDKIRNLFVE NGIVVFPGFE IASSEKIHFV CLFDENKTSQ ELERILGRLD LLDPEDGILP
TNLTAIQLID KVNEIGGFIF AAHCINDDGV LSRKMNHVWK HEGLMAAQIP GDKSIEDLKG
IENDFYRKVF LNKDPNYKRE REMAAINSSD VAKPEDIKAS GASCLIKMTN PCFASFKQAF
LDAGSRVRLN SDKPESYASA IERIRFVGGY LDSVDIELSD HLNAVIGGRG TGKSTLLECI
RYAFGLEPKT PNAIKQHKSV IDTNLGKERG LVEITLRSSV MHGRRFKVSR KHGSDPVVVD
SHGNISPYLP TDILPGIELY GQNEIYEMTR DEQSRNQLIE RFLEGEHEKF DADIADVLAK
LKDNRESIKR VLGQKDDIEA EIERLPKLLD QAKQYQALGI DEKLELIPKL EKEKQLNDQI
GEDVASVQLA IDALKNSLPD TLYLSDTNLD GLPHAELLKQ QREVLNALKT GVQQTLIQLE
QLTLNANQQL LPVKQSLSEK QQLEEQKLEL AFKDIPASQG KTGRQIGAEY QTLLKQIEQI
RPKQTTLQDR QTQIDELYNS RKKLLLELEQ HTSARASSIT KSVKRLTRKL EQKVRLTLQP
EGGRQELVNF LTGCNLEGVG PKRLAWVLEG NFSPSSLAST IRQGESELGR KFGISGTVVS
ALIRLSEVKL MELEELQLPD TMAIELNVTH GEREAVFRSI DELSTGQQCT AVLHLLLLDN
QDPLILDQPE DNLDNAFIAE RIVAELRRAK LSRQFLFATH NANIPVFGDA EWIGVLSVED
NKGLILPEQQ GAIDVPNVQA LAADILEGGK SAFNQRREKY GFV
//
