ID D0GIV0_9FUSO Unreviewed; 379 AA.
AC D0GIV0;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Cystathionine beta-lyase MetC {ECO:0000313|EMBL:EEY35976.1};
DE EC=4.4.1.8 {ECO:0000313|EMBL:EEY35976.1};
GN Name=metC {ECO:0000313|EMBL:EEY35976.1};
GN ORFNames=HMPREF0554_0148 {ECO:0000313|EMBL:EEY35976.1};
OS Pseudoleptotrichia goodfellowii F0264.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC Pseudoleptotrichia.
OX NCBI_TaxID=596323 {ECO:0000313|EMBL:EEY35976.1, ECO:0000313|Proteomes:UP000004226};
RN [1] {ECO:0000313|EMBL:EEY35976.1, ECO:0000313|Proteomes:UP000004226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0264 {ECO:0000313|EMBL:EEY35976.1,
RC ECO:0000313|Proteomes:UP000004226};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEY35976.1}.
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DR EMBL; ADAD01000029; EEY35976.1; -; Genomic_DNA.
DR RefSeq; WP_006806381.1; NZ_ADAD01000029.1.
DR AlphaFoldDB; D0GIV0; -.
DR eggNOG; COG0626; Bacteria.
DR Proteomes; UP000004226; Unassembled WGS sequence.
DR GO; GO:0004121; F:cystathionine beta-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF15; CYSTATHIONINE GAMMA-LYASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EEY35976.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000004226}.
FT MOD_RES 195
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 379 AA; 42130 MW; C195BE8F508D1B50 CRC64;
MKFGTKIIHG YNMIDESTGA SSISICQAST FHQSNIDDDQ KYTYSRFGNP TREALEEAIA
CLEKGRYGLA FSSGMAAITA VLLSFSHGDH IVMCKDVYGG AFQLANEVFP RFGIEVTFVD
ETNLDEWEKA IKENTKAFYM ETPSNPLLKI TDIKGVVNIA KKHKLLTIID NTFMTPQYQN
PIPLGVDIVI HSATKFLNGH SDVVLGMIVT DAEDIYKELK KQQIVLGALP GVEECWLLMR
GMKTMEIRMK KSSKTALKIA EYLEKHPKVE KVYYPGLKSH EGYETNKKQS LSGGAVLSFD
LGCCEKVKKF FKEVKYPIVA VSLGGVESIL SYPVKMSHAC VPEEERLKMG VTSGLVRLSV
GIEDAEDLIE DIEKALQSI
//
