ID D0GPQ2_9FUSO Unreviewed; 378 AA.
AC D0GPQ2;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Cystathionine beta-lyase MetC {ECO:0000313|EMBL:EEY33897.1};
DE EC=4.4.1.8 {ECO:0000313|EMBL:EEY33897.1};
GN Name=metC {ECO:0000313|EMBL:EEY33897.1};
GN ORFNames=HMPREF0554_0073 {ECO:0000313|EMBL:EEY33897.1};
OS Pseudoleptotrichia goodfellowii F0264.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Leptotrichiaceae;
OC Pseudoleptotrichia.
OX NCBI_TaxID=596323 {ECO:0000313|EMBL:EEY33897.1, ECO:0000313|Proteomes:UP000004226};
RN [1] {ECO:0000313|EMBL:EEY33897.1, ECO:0000313|Proteomes:UP000004226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0264 {ECO:0000313|EMBL:EEY33897.1,
RC ECO:0000313|Proteomes:UP000004226};
RA Harkins D.M., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EEY33897.1}.
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DR EMBL; ADAD01000200; EEY33897.1; -; Genomic_DNA.
DR RefSeq; WP_006808461.1; NZ_ADAD01000200.1.
DR AlphaFoldDB; D0GPQ2; -.
DR eggNOG; COG0626; Bacteria.
DR Proteomes; UP000004226; Unassembled WGS sequence.
DR GO; GO:0004121; F:cystathionine beta-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF91; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EEY33897.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000004226}.
FT MOD_RES 195
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 378 AA; 42128 MW; C76ECF4F99C476D9 CRC64;
MKFETKAIHG IRKDDGKHSG WKSTINMAST AQIENFGEEQ EFEYARVSNP TRSELEKIMA
KLENGKHAFA FSSGMAAITS LFTKFKAGDH IVLGTDIYGG TYRIMTDIFG KYNLEYTFVD
TTDLQNIEKA VKDNTVAIFI ETPSNPLLDV TDIKGVVEIA KKYELLTITD NTFMTPYLQR
PLDLGINIVV HSATKFLSGH HDILAGMVIV NSDELAEEVW FAQKAIGAIL SPFDSWLLMR
SLKTLKVRIE AAQKNTLKLI EFFKNHKAVG KVYFPTEENN KGKKIHESQA TGGGAVFSFV
LKDENKVKPF FDNLKVALSA ASLGGVETLV THPHTITHAE MPEDEKNARG ITKSLIRVAV
GIEHIDDLIE DFKNALEK
//
