ID D0KXD2_HALNC Unreviewed; 1394 AA.
AC D0KXD2;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:ACX95146.1};
GN OrderedLocusNames=Hneap_0283 {ECO:0000313|EMBL:ACX95146.1};
OS Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus
OS neapolitanus).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Halothiobacillaceae; Halothiobacillus.
OX NCBI_TaxID=555778 {ECO:0000313|EMBL:ACX95146.1, ECO:0000313|Proteomes:UP000009102};
RN [1] {ECO:0000313|EMBL:ACX95146.1, ECO:0000313|Proteomes:UP000009102}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23641 / c2 {ECO:0000313|Proteomes:UP000009102};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Davenport K., Brettin T., Detter J.C., Han C.,
RA Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA Kerfeld C., Cannon G., Heinhort S.;
RT "Complete sequence of Halothiobacillus neapolitanus c2.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001801; ACX95146.1; -; Genomic_DNA.
DR RefSeq; WP_012823182.1; NC_013422.1.
DR STRING; 555778.Hneap_0283; -.
DR KEGG; hna:Hneap_0283; -.
DR eggNOG; COG1643; Bacteria.
DR HOGENOM; CLU_001832_3_1_6; -.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000009102; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ACX95146.1};
KW Hydrolase {ECO:0000313|EMBL:ACX95146.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000009102}.
FT DOMAIN 106..269
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 311..482
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 688..711
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..709
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1394 AA; 156331 MW; 4A5123643C7C01C5 CRC64;
MNSTLNEPQD AAAPQSAPLS TEPADIIDFL RANLAELPLV DQPALSRRLA GAERALQQNR
LDAGRLAELV TAFEASAALL TERRSAELNI DYPAELPVSG QREAIMDLIR AHPVVIVAGE
TGSGKTTQLP KMLLELGFGV KGQIGHTQPR RIAARNVASR LAEELGVTGA GVVGYKVRFS
DQTRASSRVA VMTDGILLAE IHSDPDLLRY DALIIDEAHE RSLNIDFLLG IVRRLLDRRP
DFRLVITSAT IDTARFARHF AGTDASGEPQ PAPVITVAGR SFPVEYRYRS LTAPQNDNDT
ETEEERDLPA AVVAAVDELH AEAQTTGGGD ILVFLPGERE IRECAHRLGR HGLRHTEILP
LFARLSAAEQ QRIFAQHTGR RIVLTTNVAE TSLTVPGILY VIDSGLARIA RYSPRSRVQK
LAVEAISQAS ANQRAGRCGR IAPGVCIRLF DEADYAGRPA FTDPEILRTN LASVVLRMIE
LRLGEPEHFP FIEPPDSRQL AGARRLLFEL GALDERQRIT PLGRQLARLP VDPTLGRMVL
SNLSKADATS VDILIVVAFL SIQDPRERPA DHAQAADQAQ QAFRLADSDF AGILALWDQW
HTVVRHENQR KRRDWAKKHF LSYNRLLEWH DLFGQLREQA DEIGRVKLPD PLPLPVMTDG
DEAPLRARLD ALHQAMLPGL LAQIGLRDEA TRTDKNTPKD SRDQRGKKQR TPTIYIGANN
RRFQIFPGSQ LAKTQPKWLM SAEIVETTRV YARMNATINP RWIEDMAAHL TTREYSEPRW
DQRGGRVAAF ETVKLFGLPI VTKRRIDFGR IDPLGARAIF IRAALVEGEF DSGLKFWRHN
QALIDEIREI EARNRRPDLL IDDQTLFDFY ETHLPAEVYD AHTLVRWLKT ITPKQPDVLC
MTRDDLLARE PVELDPAGFP DRLSMGAFSL PLAYHFAPGS ADDGVTLRLP LAALKQIDAD
RASHLIPGLR REKIEALIRS LPKADRRHFV PAPEFAASVN ERVSVDRGGL PAQVAEQLAR
MTGHKITADA FDERRLEPHL RMRFALIDAK QTDPDKQIID ADRDLSALRA RHAAAAERAL
VERTRHRLER DDLIDWSFGE LPESLTVEEL GAELTAYPAL IDQGDCAEVR LFDAPERAVL
AHRSGVVRLM LIALGEQIRH LSQYLKQERS LDPARLQYSQ WSNTRPLPAF GLTLPQRRDA
AFDQALIARS IAKLAVDALP FIRDESTFRA RVERLKPQLD DTVRRLAAQI RTIFAQHQAL
RAKLKGRLPL SQIEAAREIA EQFDLLFYPG MIWNTPQTLL DNLPRYLTAA EKRLEKIDRH
PERDRMLRVQ FMPVCARVTD KITATAPTPE AFAALNQLHE QLEEWRVATF AQELARKGAP
GAKEIEQAIK QLSH
//
