ID D0N0D7_PHYIT Unreviewed; 137 AA.
AC D0N0D7;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase catalytic domain-containing protein {ECO:0000259|Pfam:PF00389};
GN ORFNames=PITG_04032 {ECO:0000313|EMBL:EEY67100.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY67100.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028122; EEY67100.1; -; Genomic_DNA.
DR RefSeq; XP_002905748.1; XM_002905702.1.
DR AlphaFoldDB; D0N0D7; -.
DR STRING; 403677.D0N0D7; -.
DR EnsemblProtists; PITG_04032T0; PITG_04032T0; PITG_04032.
DR GeneID; 9479366; -.
DR KEGG; pif:PITG_04032; -.
DR VEuPathDB; FungiDB:PITG_04032; -.
DR HOGENOM; CLU_1869161_0_0_1; -.
DR InParanoid; D0N0D7; -.
DR OrthoDB; 6392at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 28..74
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
SQ SEQUENCE 137 AA; 15706 MW; 33862E734FD9333F CRC64;
MSPPIAPRKI FFTRNWPYAI ANWRFYYHID VEACKACSIR VGHTPGVLDM AVAEIAVALT
FAAKRRVLEC AASAKNELAI MKPSAVLINT GRWTKMLSWK LSRARRSQRP AWTRRPQSRF
LPHIRCSRLI TASYFPT
//
