ID D0N4W3_PHYIT Unreviewed; 1079 AA.
AC D0N4W3;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE SubName: Full=Myosin-like protein {ECO:0000313|EMBL:EEY69921.1};
GN ORFNames=PITG_06450 {ECO:0000313|EMBL:EEY69921.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY69921.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; DS028125; EEY69921.1; -; Genomic_DNA.
DR RefSeq; XP_002998568.1; XM_002998522.1.
DR AlphaFoldDB; D0N4W3; -.
DR STRING; 403677.D0N4W3; -.
DR EnsemblProtists; PITG_06450T0; PITG_06450T0; PITG_06450.
DR GeneID; 9471669; -.
DR KEGG; pif:PITG_06450; -.
DR VEuPathDB; FungiDB:PITG_06450; -.
DR eggNOG; KOG0164; Eukaryota.
DR HOGENOM; CLU_000192_7_7_1; -.
DR InParanoid; D0N4W3; -.
DR OMA; NDMWRSC; -.
DR OrthoDB; 49487at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF679; UNCONVENTIONAL MYOSIN IC; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 1..724
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 884..1078
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 581..603
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 98..105
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1079 AA; 123993 MW; A9D5501FB00A361C CRC64;
MKDLLMVDAV DEDHVVNELV TRYRQGYVYM FLGPVLIAMN PYKMLRQPNG DSIYARNMID
EFQGKELHVC EPHPFALAEN AYSSLMRFGL DQSLLITGES GSGKTETSKH VMRYLTTIST
RSRAKSAVMA NRRMSVAQRK EADDMTSHVT DVLWGSNPVL EAFGNAQTIR NNNSSRFGKY
IVLQMNRVGQ VIGGYIDNYL LERSRVIRQA EGERNFHAFY QLMSGATATD REAWQLPGSA
EEFDVLGNED ATIDGVDDAE NYRNVRENMT AVGITDEEQR AIFQQLSAIL WLGNVQFKQT
TDEAHNPRAA IEDPAAREAL AKAAGLMGID KDKLEALLTF RIVNIYREDQ KVLFDARQAK
KVCDSIMRSL YEKIFDWIVA RINKNVTCKK RDINNSIGIL DIYGFEIFEV NAFEQLCINY
VNEKLQQLFI SQTLESEQEG YRREGLSWQN IKFFNNQVVC DLIEDPKQHG IFPLLDEQCA
IARLSDLELI ERYNSEHSRN PHYMASRVRG PNFGIVHYAG KVEYDVTLFF DANVDTFFND
LQDGMEQSSN AFVRAVFLDK RSKETKLKRP PSTSQQFRTQ VADLLKKLDG CNPHYIRCIK
PNEKKQPLAV NKELVAEQVR YLGLVQNLSV RRQGFCYSQP YAPFIKRYSF LSESTWPAPV
AHSSRKAAVD LLTTAGLGVR DPNNKDELIP FQEDSDTLGC FSLGRNKIFL RHPQALSALE
ILREERIPVI VNIIENAWRR YMNRLALKEF QTASKQLLSA YDAVWRNCQD RRKRVPGASD
KEHVAKIYGS WEAVSTKLLN VNNSRLVKNL KAEEELNSIV FMQSFVQART QRREFLKLRH
AQIVFSKRYR GLNTRKQLAN DMWKACKVAL LGVRTEFERY LGKKKRRRDS LDRTYQGDYI
GVNRYPAYAA ILQAHTEGRG SKAGSGRGQK EKLLFLDTVE KVNERWAHQT RVLMISESRV
FNLKADKIQQ PKERRVFELS RLSSVAMSTQ PDNYLIFRVK GEIDLMVQVS QKTEVVQALR
ARLQKGYGRE LTVEFSDELD FYAAKGKQLK VKFAFDRSMK DSEWSKVDRH TMQVKVGIV
//
