ID D0NEX5_PHYIT Unreviewed; 773 AA.
AC D0NEX5;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=WW domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PITG_10265 {ECO:0000313|EMBL:EEY56764.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY56764.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS028135; EEY56764.1; -; Genomic_DNA.
DR RefSeq; XP_002902092.1; XM_002902046.1.
DR AlphaFoldDB; D0NEX5; -.
DR STRING; 403677.D0NEX5; -.
DR EnsemblProtists; PITG_10265T0; PITG_10265T0; PITG_10265.
DR GeneID; 9473903; -.
DR KEGG; pif:PITG_10265; -.
DR VEuPathDB; FungiDB:PITG_10265; -.
DR eggNOG; ENOG502RMIQ; Eukaryota.
DR HOGENOM; CLU_017218_0_0_1; -.
DR InParanoid; D0NEX5; -.
DR OMA; VNIFQPM; -.
DR OrthoDB; 52592at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR17616:SF8; YES-ASSOCIATED PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR17616; YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT DOMAIN 520..553
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 600..682
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 681..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 255..282
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 336..384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 9..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 773 AA; 84447 MW; 8D8AB49E01A26CBC CRC64;
MERFEASTPQ HQGHPSYPPS ASPLSVSSPS SLTTSASPPI PFSAIQSSSD TGEDDVVKAN
DSVLIPPPES DTNTSIPDSN MLSERQLIAR GRVLLRAYQS QKKLWLQNGE YDSTEVPQTL
IGSQVNIFQP MISSNGEYST IEYSSPTKKA VATAEAPSID TKLEDLPLPP PHPSFPPPSS
IVSGLSNFSI GVLPPSELKV HQPLSGNQSE KSWADFMQLL KANGHTMDSV DAQLAQIWEE
LVSAYINARG PQPSVDKLSE AVTQLLQQKR EAESAIAKLT EVLGSRAFLA GKLSDDAVQF
VSNQLRLELE ASQILVDKVK TESISLKEES TATVNGNSRA DEIARLRQQL QDKEEELQAS
HSAVAKLEDQ LTRQQESAIE TQTKFERALN VKFREIDALC SGIELPVDYE RIKTKEGVTG
YKRIGGDSSN ELEDPRIRIA LQQRSTSRTE DKDNVSVATE ITSSSSAQRP RGISAMAAAP
DNVLRRSFST PHISHDSNVF EDIHVPPDDG RKHTIEDFST PLPAGWEMRV TASGAVFFFN
KYTTTTTWTD PRLLTPSSAS QKPLARNSSA TTTESRASRS NSTVVNTETI RKEEEEGVKY
LDVVFEASGP IGIHFQANVP DSGATVRGLL PDMAAANKNS LQPFDELVAV NKTPVDAAPF
RHVMLLLQGG LRPLTLTFKR DLSSPQRPMP PLQDAPPSDS SSSDGFDSHL DEEVLIDEGT
VVDLEQLRVP VELPPTVSEE EEDDDMNVAD VIITNIFSLF WKSPETTGEV QTV
//
