ID D0NID9_PHYIT Unreviewed; 1022 AA.
AC D0NID9;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Glucosidase II subunit alpha {ECO:0000256|ARBA:ARBA00042895};
GN ORFNames=PITG_11712 {ECO:0000313|EMBL:EEY59224.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY59224.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- PATHWAY: Glycan metabolism; N-glycan metabolism.
CC {ECO:0000256|ARBA:ARBA00004833}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR EMBL; DS028139; EEY59224.1; -; Genomic_DNA.
DR RefSeq; XP_002901238.1; XM_002901192.1.
DR AlphaFoldDB; D0NID9; -.
DR STRING; 403677.D0NID9; -.
DR EnsemblProtists; PITG_11712T0; PITG_11712T0; PITG_11712.
DR GeneID; 9470758; -.
DR KEGG; pif:PITG_11712; -.
DR VEuPathDB; FungiDB:PITG_11712; -.
DR eggNOG; KOG1066; Eukaryota.
DR HOGENOM; CLU_000631_7_0_1; -.
DR InParanoid; D0NID9; -.
DR OMA; QAGIWYP; -.
DR OrthoDB; 5480935at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06603; GH31_GANC_GANAB_alpha; 1.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 2.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF54; BCDNA.GH04962; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..1022
FT /note="Glucosidase II subunit alpha"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003012077"
FT DOMAIN 101..382
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 428..777
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 785..879
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
FT REGION 249..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1022 AA; 115128 MW; 37E967BD5F6F6C42 CRC64;
MLSRRLLVLV AAAALASSAD AVDRSKFRTC EKTQFCNKFR NVQRQELPSK FYVERASIRS
DSDANLVRFL VEDAGQKGGV PLAGSLAFVL NADRAVVPAL RVRLQEKFEN PKDPKIRWTS
DDILVPAAEE TRPLRQLTVK EAGLKTSINE DNVLLFAPET QGATQVVAAL KLGEGSFGVD
LYLDGEKVVS TNDDGLFHYE IRQDRVDSAA QGEAAADQAA VDAHEGKTIV DYGEDGLAIY
DDGTVQKKEE QSATTTATAG ADGNVEGWEE SFGGHTDKKK FGPSSIGLDV SFHGSAEAPR
SLYGIPEHAT DFVLKDTIEP NDEGEGKRRV VTDPYRLYNL DVFEYELDNP MALYGAIPVL
VAPNKENTVG MFWNNPSETF VDTWTDEETN SKSSHWLSES GVFDLFLLAG PSSADLFSQY
TLLTGRAQLP PLFALGYHQC RWNYKNEADM ARVDAGFDEH LIPYDVLWLD IEHTDGKRYF
TWDEHAFPTP KNMQESVART GRKIVTIVDP HIKVSQSKDK QPYYIHTEAE ELGLFVKDEQ
GNDFKGWCWP GESSYVDFTS PKARAWWRHQ FRYENYQGST KHLYTWNDMN EPSVFNGPEV
SMRKGCMSLA GVEHREWHNL YGILFQRSTM EGQLVRQQPP PEPLSAFGEE LQLRSDMQRP
FVLSRAFSAG SQRYGAIWTG DNTAEWGHLR YATKMLLSMS VAGLTFVGAD VGGFFGNPPT
ELLTRWNQAA VYQPFFRGHA HHDSARREPW VFGEPTTSRI RAAIRERYSL LPYIYTLFHT
CYARGMPIMR PLWAHFTLEP QSFSEEDQYL LGDALLVKPI VEEGVEATHV FLPSDNAQDK
TVWYQVTDGY KRFFGGKTYA NVPAPLDAIP VFQRGGTILP RKQRVRRSSE LMRDDPLTLV
VALDQRLEAR GDLYVDDERS LAAELEGEGT VVSFHQTKEG LRSTATAATS QGKRYTSLMW
VERIDVYGFQ SEANVPKQVL VGSERAVDFQ YDAASDRLVL RKPQVLVTDD WELRFVYDQA
LE
//
