ID D0NK09_PHYIT Unreviewed; 882 AA.
AC D0NK09;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=PITG_12988 {ECO:0000313|EMBL:EEY59846.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY59846.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
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DR EMBL; DS028142; EEY59846.1; -; Genomic_DNA.
DR RefSeq; XP_002900531.1; XM_002900485.1.
DR AlphaFoldDB; D0NK09; -.
DR STRING; 403677.D0NK09; -.
DR EnsemblProtists; PITG_12988T0; PITG_12988T0; PITG_12988.
DR GeneID; 9478487; -.
DR KEGG; pif:PITG_12988; -.
DR VEuPathDB; FungiDB:PITG_12988; -.
DR eggNOG; ENOG502RXER; Eukaryota.
DR HOGENOM; CLU_016286_0_0_1; -.
DR InParanoid; D0NK09; -.
DR OMA; TVECQST; -.
DR OrthoDB; 54053at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00065; FYVE_like_SF; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 288..349
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 353..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 799..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..401
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..498
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..566
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..603
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 882 AA; 99707 MW; 72FC8E378DA76034 CRC64;
MTKTLPLPPR FFKRPELTER EEQYLVGKAK DSAKALVDAT RNNEGPVRWE EAGMHRGVQM
YKGEARYPEA VVGESISYGC GATTIQSTLD EVADFFDLST DAKVAAFVEC NADVLDAQLL
YVIEDPSLLN DPKYTVRGQR SGSSKMLNAN QVTIKWFASE MPSKLLKNRD FLTVECQSTF
MDVSGRRGWV RSYHSIKLPC CPELSDYNLV RGSFYHTGYV FVESERPGFL DVIFSAQVNM
KGSMKVPTPL FMTIQKKRLS GIADLQKMIT RRRLGAQRFL GDLELVPKSQ RTRCNLCSAK
FGLITRKARC RKCGEVVCAS ACSTEWEVAI PGQGVRKVRV CFKCAQNTDP SVFEDLPPSE
QYSETNSAHD DEPPVMSVRA PGYQYERYNR SNSGSPTSRR RGQPSRDSDE YDSQGRGRRD
HSGRRGPYNN SYEESYSQSD SYQDPDPEYP RTMEMPGEYG KVSLDSDRFT NDSGEYDDNP
PSSRRRRDDR KYDPRNPDMY DHQTYGVSPP QYRDEEQRRA LQRQQRALQQ HQNKQRLLQR
QQQQQEALMR RRQEQNIEEP DNYRDELESM SLSSSEFSQF SQSSGASSGA PSFLTSSLLA
QHTKQMGKPG PVTKNERNAA RRVVQEERTR RSKPARDSEP EPERPPPPSL SSDRPLTRLE
LLQVAQWEQQ EAMFRNQEPL DLEVEAAEIV LTKPHRRRTG SSEGSAKRRG PELPAFFRSP
HSSAHSQGHG APTGESSLSK LPTFPTNSGQ TVSVADDEDR LDYSSGRDDS INGLSMNFGS
LLRPEDLRPT EESMCLSLDS SGQEHSTMGD SDANPGKAGA SAAKDRADTS KTTVVKLYQR
ILELTNKQHE LEAQPESDPN EKKEIAQELE VLYEKLHSEV EI
//
