ID D0NS10_PHYIT Unreviewed; 743 AA.
AC D0NS10;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN ORFNames=PITG_15905 {ECO:0000313|EMBL:EEY63551.1};
OS Phytophthora infestans (strain T30-4) (Potato late blight agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=403677 {ECO:0000313|EMBL:EEY63551.1, ECO:0000313|Proteomes:UP000006643};
RN [1] {ECO:0000313|Proteomes:UP000006643}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX PubMed=19741609; DOI=10.1038/nature08358;
RG The Broad Institute Genome Sequencing Platform;
RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M.,
RA Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O.,
RA Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A.,
RA Baxter L., Beynon J., Boevink P.C., Bollmann S.R., Bos J.I., Bulone V.,
RA Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S.,
RA Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S.,
RA Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J.,
RA Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S.,
RA Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P.,
RA Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S.,
RA Nusbaum C.;
RT "Genome sequence and analysis of the Irish potato famine pathogen
RT Phytophthora infestans.";
RL Nature 461:393-398(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC with release of beta-D-glucose.; EC=3.2.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00000448};
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DR EMBL; DS028156; EEY63551.1; -; Genomic_DNA.
DR RefSeq; XP_002898138.1; XM_002898092.1.
DR AlphaFoldDB; D0NS10; -.
DR STRING; 403677.D0NS10; -.
DR EnsemblProtists; PITG_15905T0; PITG_15905T0; PITG_15905.
DR GeneID; 9475694; -.
DR KEGG; pif:PITG_15905; -.
DR VEuPathDB; FungiDB:PITG_15905; -.
DR eggNOG; ENOG502QQ55; Eukaryota.
DR HOGENOM; CLU_004542_5_2_1; -.
DR InParanoid; D0NS10; -.
DR OMA; NFPGLCV; -.
DR OrthoDB; 5485475at2759; -.
DR Proteomes; UP000006643; Partially assembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR026891; Fn3-like.
DR InterPro; IPR002772; Glyco_hydro_3_C.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR30620:SF16; LYSOSOMAL BETA GLUCOSIDASE; 1.
DR PANTHER; PTHR30620; PERIPLASMIC BETA-GLUCOSIDASE-RELATED; 1.
DR Pfam; PF14310; Fn3-like; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR Pfam; PF01915; Glyco_hydro_3_C; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SMART; SM01217; Fn3_like; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000006643};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..743
FT /note="beta-glucosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003013690"
FT DOMAIN 638..712
FT /note="Fibronectin type III-like"
FT /evidence="ECO:0000259|SMART:SM01217"
SQ SEQUENCE 743 AA; 81010 MW; F57C28C70403F5EE CRC64;
MLKSWFAAVC CLAVSLTGTP FVSADEWDAQ TDVIIESMDE DQLVGQMVQV AFSRFFNKDK
TFDEDKFRAY AKLKIGSYLS GPWQSGSYNG KYGWTAQEWR DVLSRAQEIV KEENDGHPFI
FGIDSLHGAG FTSGAVLFGQ PINGAATFNP DLAYEMGRIS GRDTLAAGTP WIFGPMLEIS
QNPLWPRVYE TFGEDPVLVS AISEALIKGI QSNNGSAACM KHWIGYSKTP TGHDKDPVTL
SDLDLLNYFL PPFKAAVDAG VMSAMENYIS VNGIPTIANH KLMNKLLRED LGFEGLTVVR
PLASSDYGFI NATKALIANE PSYLNRVKES ARRVIKLKLQ LGLYDNAVPG ADLVDQVGND
EDKAATLNSA RESIVLLQNN DSVLPIPETA KVLLTGHSAD NVGFQCGGWS LSQQGYSGND
MFPNGITVKD EFQAISNETL TYFNGLNYTG VYNESDLAQA KEYASQADYT VAVIGEHSYT
EKTYGDINDL ALPAGQIEYV SELASTGTKV IVVLVGGRPR LLGELPNNVH AVINAMLPCE
LGGQAIAEII YGRVNPSGRM PITYPKDAGN ILMPYNHLVS TQCATGYCEM QWEFGHGLSY
TDFTYSDMTL SRSNVTSITE SVDVSVVVTS AGTVAGKETV MLFLTQPFRT ISVPEVKQLK
KFTKVDLKAG ESTTVKFTLS ADDWSVYYPQ IGSGLKKVAE DADYVLAIKP ETDCDVYNKT
AVANPLCATF TLQTGEHPYG SFE
//
