ID   D0QWE7_DROMI            Unreviewed;       683 AA.
AC   D0QWE7;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=GA14176 {ECO:0000313|EMBL:ACN94646.1};
GN   ORFNames=GA14176 {ECO:0000313|EMBL:ACN94646.1};
OS   Drosophila miranda (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7229 {ECO:0000313|EMBL:ACN94646.1};
RN   [1] {ECO:0000313|EMBL:ACN94646.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MSH22 {ECO:0000313|EMBL:ACN94646.1};
RX   PubMed=19859648; DOI=10.1007/s00239-009-9298-2;
RA   Marion de Proce S., Halligan D.L., Keightley P.D., Charlesworth B.;
RT   "Patterns of DNA-sequence divergence between Drosophila miranda and D.
RT   pseudoobscura.";
RL   J. Mol. Evol. 69:601-611(2009).
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DR   EMBL; FJ821026; ACN94646.1; -; Genomic_DNA.
DR   RefSeq; XP_017143234.1; XM_017287745.1.
DR   AlphaFoldDB; D0QWE7; -.
DR   GeneID; 108156343; -.
DR   KEGG; dmn:108156343; -.
DR   OMA; HIQGESY; -.
DR   OrthoDB; 5488678at2759; -.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012959; CPL_dom.
DR   InterPro; IPR033133; PUM-HD.
DR   InterPro; IPR040059; PUM3.
DR   InterPro; IPR001313; Pumilio_RNA-bd_rpt.
DR   PANTHER; PTHR13389:SF0; PUMILIO HOMOLOG 3; 1.
DR   PANTHER; PTHR13389; UNCHARACTERIZED; 1.
DR   Pfam; PF08144; CPL; 1.
DR   Pfam; PF00806; PUF; 2.
DR   SMART; SM00025; Pumilio; 4.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50302; PUM; 1.
DR   PROSITE; PS50303; PUM_HD; 1.
PE   4: Predicted;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          95..446
FT                   /note="PUM-HD"
FT                   /evidence="ECO:0000259|PROSITE:PS50303"
FT   REPEAT          159..194
FT                   /note="Pumilio"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00317"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          527..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..550
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        551..574
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   683 AA;  76617 MW;  E904719ECAED0D87 CRC64;
     MVSSKEADKT RPPRPKSNFK PGNNKPNNKF KSAPKFAKKS DNTKAKPGAG HNKFAGKPVC
     SGQPEKQDWN KFKQEKKELK LKRKSTRDTY EITKEAKQIY EKLRCRKTEN KDQLVEQMFK
     ILNVGDTISK IVKAHDTARV LQCMLKHATP ALRAEISDKL LPYAVEMCQS KYAQFCVQRM
     LKYGAPATKS KLVDSLFGHI VRLAGHSIAS GLLDVMYQGG TRQQRTHMRQ EFYGDLYRKA
     KDSSVKTLSD TYKEATNMKA SILGSVKANL DHVANKNLVD SSLVHCVMLE YLRACEDEEE
     KLEETVTAFA ALVPHMLSTK EGSEAAVICF YKSTPKNRRA IIKNIKEHLL KIATHEHGHV
     FLISLLNALD DTKATKKAIY DHLHGDLKQL VGNQYGRRVV QWLVAPGDTT CFHPTFIRVI
     EEGLAFGKKE KETRRKEIFE QIEAPIGEAI VEDAAFWLSN SHIGLVTADI LNHIQGESYQ
     KAVEAFAQVV VQPDWRITAD AAGAQPLQQK KGHQDVEDII AEATKQRKKL TKVEESSDED
     DEESAKEEAD KEEADADIIK PKKAKKEPKP AKEEPAKPLV TGIEEAGMHI VLKKILKNDG
     KQQVEEGRSF GEQILKHLTS DGLKAWLSVN RGCFILLKLV EERPQLLDTC RTAIEAEEEV
     GQLLKSQKTL GAKLLAGKLN IGK
//