ID D0R374_LACJF Unreviewed; 460 AA.
AC D0R374;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=HlyC/CorC family transporter {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=FI9785_661 {ECO:0000313|EMBL:CAX66537.1};
OS Lactobacillus johnsonii (strain FI9785).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=633699 {ECO:0000313|EMBL:CAX66537.1, ECO:0000313|Proteomes:UP000002627};
RN [1] {ECO:0000313|EMBL:CAX66537.1, ECO:0000313|Proteomes:UP000002627}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FI9785 {ECO:0000313|EMBL:CAX66537.1,
RC ECO:0000313|Proteomes:UP000002627};
RX PubMed=19767436; DOI=10.1128/JB.01182-09;
RA Wegmann U., Overweg K., Horn N., Goesmann A., Narbad A., Gasson M.J.,
RA Shearman C.;
RT "Complete genome sequence of Lactobacillus johnsonii FI9785, a competitive
RT exclusion agent against pathogens in poultry.";
RL J. Bacteriol. 191:7142-7143(2009).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC {ECO:0000256|ARBA:ARBA00006337}.
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DR EMBL; FN298497; CAX66537.1; -; Genomic_DNA.
DR RefSeq; WP_012845881.1; NC_013504.1.
DR AlphaFoldDB; D0R374; -.
DR GeneID; 83570068; -.
DR KEGG; ljf:FI9785_661; -.
DR HOGENOM; CLU_015237_4_0_9; -.
DR Proteomes; UP000002627; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR43099; UPF0053 PROTEIN YRKA; 1.
DR PANTHER; PTHR43099:SF2; UPF0053 PROTEIN YRKA; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM00116; CBS; 2.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51846; CNNM; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703}; Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000002627};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT TRANSMEM 6..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 142..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..209
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 228..290
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 293..350
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 460 AA; 51703 MW; FA65E1C30BEA453A CRC64;
MSTSTITTNL IVIFITFLIA IFFVVAEFAL VQTRSSQLED MLANGQGNPK KLKRALHMVH
NLNESLSTTQ VGTTLVGVIL GWIGQGTIEE LLTDVFKMTP WFGAKTSGVL GATLGVVLLT
YLEVVVTEIV PKNIAIDMPV KCLMAVVTPL AAFHTIVYPF VWLLNHSANG LLHLLGMQSA
DEESEVYSQS EILRLSRNAV TGGSLDKDDL LYMERAFELN DKVAKDIMTD RTQLQVLNAT
DDVKTALEKY IKDGFSRFPV VRDNDKDDVV GYVYAYDIVS QDQENPNVPI TRIIRAIITV
PESMLIQDIL KLMIKKHTPI VLVVDEYGGT SGIVTDKDIY EELFGSIKDE IDDVSDEYIV
RDDHGNIHVS GKTTLYDFER YFHTKLKAFE DSDIITIGGY MMEHYPNLKR GESVDLEGFK
FKLVNIEQGF MRWFIVSKID QASENDDSEN SDQNDKEKDK
//
