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Database: UniProt
Entry: D0R846_9BURK
LinkDB: D0R846_9BURK
Original site: D0R846_9BURK 
ID   D0R846_9BURK            Unreviewed;       207 AA.
AC   D0R846;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   RecName: Full=Protein RecA {ECO:0000256|ARBA:ARBA00015553, ECO:0000256|RuleBase:RU000526};
DE   AltName: Full=Recombinase A {ECO:0000256|RuleBase:RU000526};
DE   Flags: Fragment;
GN   Name=recA {ECO:0000313|EMBL:CBA73290.1};
OS   Burkholderia sp. JPY350.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia.
OX   NCBI_TaxID=667634 {ECO:0000313|EMBL:CBA73290.1};
RN   [1] {ECO:0000313|EMBL:CBA73290.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=JPY350 {ECO:0000313|EMBL:CBA73290.1};
RA   Bontemps C., Elliott G.N., Simon M.F., dos Reis F.B., Gross E., Neto N.E.,
RA   Lawton R., de Fattima Loureiro M., de Faria S.M., Sprent J.I., James E.K.,
RA   Young P.W.;
RT   "Burkholderia species are ancient symbionts of legumes.";
RL   Mol. Ecol. 0:0-0(2009).
CC   -!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of single-
CC       stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex
CC       DNA, and the ATP-dependent hybridization of homologous single-stranded
CC       DNAs. It interacts with LexA causing its activation and leading to its
CC       autocatalytic cleavage. {ECO:0000256|ARBA:ARBA00025580}.
CC   -!- SIMILARITY: Belongs to the RecA family. {ECO:0000256|ARBA:ARBA00009391,
CC       ECO:0000256|RuleBase:RU004527}.
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DR   EMBL; FN543854; CBA73290.1; -; Genomic_DNA.
DR   AlphaFoldDB; D0R846; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   CDD; cd00983; RecA; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013765; DNA_recomb/repair_RecA.
DR   InterPro; IPR020584; DNA_recomb/repair_RecA_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR049428; RecA-like_N.
DR   InterPro; IPR020588; RecA_ATP-bd.
DR   InterPro; IPR020587; RecA_monomer-monomer_interface.
DR   NCBIfam; TIGR02012; tigrfam_recA; 1.
DR   PANTHER; PTHR45900:SF1; MITOCHONDRIAL DNA REPAIR PROTEIN RECA HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR45900; RECA; 1.
DR   Pfam; PF00154; RecA; 1.
DR   PRINTS; PR00142; RECA.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00321; RECA_1; 1.
DR   PROSITE; PS50162; RECA_2; 1.
DR   PROSITE; PS50163; RECA_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004527};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|RuleBase:RU004527};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172,
KW   ECO:0000256|RuleBase:RU004527};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|RuleBase:RU000526};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004527};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU004527};
KW   SOS response {ECO:0000256|RuleBase:RU000526}.
FT   DOMAIN          1..142
FT                   /note="RecA family profile 1"
FT                   /evidence="ECO:0000259|PROSITE:PS50162"
FT   DOMAIN          147..207
FT                   /note="RecA family profile 2"
FT                   /evidence="ECO:0000259|PROSITE:PS50163"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CBA73290.1"
FT   NON_TER         207
FT                   /evidence="ECO:0000313|EMBL:CBA73290.1"
SQ   SEQUENCE   207 AA;  22285 MW;  159A2F27C7C0F1BB CRC64;
     GGLPRGRVVE IYGPESSGKT TLTLQVIAEM QKLGGTAAFI DAEHALDVQY AAKLGVNVPE
     LLISQPDTGE QALEITDALV RSGSIDMIVI DSVAALVPKA EIEGEMGDSL PGLQARLMSQ
     ALRKLTGTIK KTNCMVIFIN QIRMKIGVMF GNPETTTGGN ALKFYSSVRL DIRRIGSIKK
     NDEVIGSETR VKVVKNKVSP PFREAVF
//
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