ID D0SAI1_ACIJO Unreviewed; 402 AA.
AC D0SAI1;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase {ECO:0000313|EMBL:EEY97418.1};
GN ORFNames=HMPREF0016_00501 {ECO:0000313|EMBL:EEY97418.1};
OS Acinetobacter johnsonii SH046.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=575586 {ECO:0000313|EMBL:EEY97418.1, ECO:0000313|Proteomes:UP000012047};
RN [1] {ECO:0000313|Proteomes:UP000012047}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SH046 {ECO:0000313|Proteomes:UP000012047};
RX PubMed=23144699; DOI=10.1371/journal.pone.0046984;
RA Peleg A.Y., de Breij A., Adams M.D., Cerqueira G.M., Mocali S.,
RA Galardini M., Nibbering P.H., Earl A.M., Ward D.V., Paterson D.L.,
RA Seifert H., Dijkshoorn L.;
RT "The success of Acinetobacter species; genetic, metabolic and virulence
RT attributes.";
RL PLoS ONE 7:E46984-E46984(2012).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the UbiH/COQ6 family.
CC {ECO:0000256|ARBA:ARBA00005349}.
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DR EMBL; GG704964; EEY97418.1; -; Genomic_DNA.
DR RefSeq; WP_005399804.1; NZ_GG704964.1.
DR AlphaFoldDB; D0SAI1; -.
DR eggNOG; COG0654; Bacteria.
DR HOGENOM; CLU_009665_8_1_6; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000012047; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010971; UbiH/COQ6.
DR NCBIfam; TIGR01988; Ubi-OHases; 1.
DR PANTHER; PTHR43876; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43876:SF7; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..357
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 402 AA; 44325 MW; CBB927EE2CA64728 CRC64;
MQQEVIIVGG GMVGLSLALM LAKQNIVVKL LEAIKYPNYD DVNLAPYHSS FDARNSALSR
RTVQIYQELG LWNALQEHAT PILEVNITEQ GSFGKARLKA EQEKVESFGQ VIENAWLGRV
LLTEVQKQPL IELIDGVKVT QLIQDADMAY IEASRGEEQL SLQAKLVIAA DGRDSFCRKA
LGIGASEHDY DQVAIVTTVQ TSKPHNHVGF ERFSSLGPLA LLPLPGEYHR SVVWPVKKGT
EGEWLGDEND QHFLDALQET YGDRAGKFQK TGKRFSFPLS QVLAEKQAVG RVVLMGNAAH
TIHPVAGQGF NLCMRDAHVL VRFLTEQIAQ NADLGDAAML QAYEASRLTD QQRVIKFCDS
VVRGFSNSNP ILKFIRNTGL VAFDTIPGIK PLVANYAMGL KA
//
