ID D0TNH0_9BACE Unreviewed; 499 AA.
AC D0TNH0;
DT 15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Succinate CoA transferase {ECO:0000313|EMBL:EEZ05664.1};
DE EC=2.8.3.- {ECO:0000313|EMBL:EEZ05664.1};
GN ORFNames=HMPREF0102_00663 {ECO:0000313|EMBL:EEZ05664.1};
OS Bacteroides sp. 2_1_22.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=469588 {ECO:0000313|EMBL:EEZ05664.1, ECO:0000313|Proteomes:UP000005775};
RN [1] {ECO:0000313|EMBL:EEZ05664.1, ECO:0000313|Proteomes:UP000005775}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_1_22 {ECO:0000313|EMBL:EEZ05664.1,
RC ECO:0000313|Proteomes:UP000005775};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Feldgarden M., Earl A., Young S.K., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Bochicchio J., Borenstein D., Chapman S., Chen Z.,
RA Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heilman E., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA McDonald J., Allen-Vercoe E., Strauss J., Ambrose C., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides sp. strain 2_1_22.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
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DR EMBL; GG705173; EEZ05664.1; -; Genomic_DNA.
DR RefSeq; WP_004312851.1; NZ_GG705173.1.
DR AlphaFoldDB; D0TNH0; -.
DR HOGENOM; CLU_019748_3_0_10; -.
DR Proteomes; UP000005775; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR017821; Succinate_CoA_transferase.
DR NCBIfam; TIGR03458; YgfH_subfam; 1.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Transferase {ECO:0000313|EMBL:EEZ05664.1}.
FT DOMAIN 5..211
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 317..458
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
FT ACT_SITE 284
FT /note="5-glutamyl coenzyme A thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-1"
FT BINDING 354
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 374
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 378
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
FT BINDING 398
FT /ligand="CoA"
FT /ligand_id="ChEBI:CHEBI:57287"
FT /evidence="ECO:0000256|PIRSR:PIRSR617821-2"
SQ SEQUENCE 499 AA; 53993 MW; 13D1E6A37A4720B9 CRC64;
MSLNRISAAE AASLIKHGYN IGLSGFTPAG TAKAVTAELA KIAEAEHAKG NPFQVGIFTG
ASTGESCDGV LSRAKAIRYR APYTTNADFR KAVNNGEIAY NDIHLSQMAQ EVRYGFMGKV
NVAIIEACEV TPDGKIYLTA AGGISPTICR LADQIIVELN SAHSKSGMGM HDVYEPLDPP
YRREIPIYKP SDRIGLPYVQ VDPKKIIGVV ETNWPDEARS FAAADPLTDK IGQNVADFLA
ADMKRGIIPS TFLPLQSGVG NIANAVLGAL GRDKTIPPFE MYTEVIQNSV IGLIREGRIK
FGSACSLTVT NDCLEGIYND MDFFRDKLVL RPSEISNSPE IVRRLGIISI NTAIEVDLYG
NVNSTHIGGT KMMNGIGGSG DFTRNAYISI FTCPSVAKEG KISAIVPMVS HHDHTEHDVN
IVITEQGVAD LRGKSPKERA QAIIENCAHP DYKELLWDYL KLAGNRAQTP HAIQAALGMH
AELAKSGDMK NTNWAEYAK
//
