ID   D0U6L5_9VIRU            Unreviewed;       254 AA.
AC   D0U6L5;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Non-structural protein {ECO:0000313|EMBL:ACX85475.1};
DE   Flags: Fragment;
OS   HMO Astrovirus C.
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC   Stellavirales; Astroviridae; Mamastrovirus.
OX   NCBI_TaxID=682384 {ECO:0000313|EMBL:ACX85475.1};
RN   [1] {ECO:0000313|EMBL:ACX85475.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NE-3010 {ECO:0000313|EMBL:ACX85475.1};
RX   PubMed=19692544; DOI=10.1099/vir.0.014449-0;
RA   Kapoor A., Li L., Victoria J., Oderinde B., Mason C., Pandey P.,
RA   Zaidi S.Z., Delwart E.;
RT   "Multiple novel astrovirus species in human stool.";
RL   J. Gen. Virol. 90:2965-2972(2009).
CC   -!- SUBCELLULAR LOCATION: Host membrane {ECO:0000256|ARBA:ARBA00004301};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004301}.
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DR   EMBL; GQ415662; ACX85475.1; -; Genomic_RNA.
DR   GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.70.270; -; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001205; RNA-dir_pol_C.
DR   Pfam; PF00680; RdRP_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Ribosomal frameshifting {ECO:0000256|ARBA:ARBA00022758};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Viral RNA replication {ECO:0000256|ARBA:ARBA00022953}.
FT   DOMAIN          3..164
FT                   /note="RNA-directed RNA polymerase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00680"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ACX85475.1"
SQ   SEQUENCE   254 AA;  29429 MW;  5D6E8DEA945181B7 CRC64;
     MPNEVFRAIK DFRFSCLRGD LQTKENRDVY NWYCENIFRR YVMLPSGEVT IQDRGNPSGQ
     ISTTMDNNIC NVFFQAFEFA YLNTELDSDE LKENWDKYDS LIYGDDRLTT TPILCDNYVD
     RVIKMYADVF GMWVKREKVK VSNEINGLTF CGFTVQESNG LFVPIPTDTD KLLAGLITPI
     KKLPDILSLY GKLLCYRILG HNLPDDHKFK NYILVALEVV ARHIRASGGE EPYYITDSML
     DRLWRGGPKQ SHGW
//