ID D1A2P3_THECD Unreviewed; 465 AA.
AC D1A2P3;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Zn-dependent protease and their inactivated protein-like protein {ECO:0000313|EMBL:ACY97841.1};
GN OrderedLocusNames=Tcur_2275 {ECO:0000313|EMBL:ACY97841.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY97841.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY97841.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
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DR EMBL; CP001738; ACY97841.1; -; Genomic_DNA.
DR RefSeq; WP_012852625.1; NC_013510.1.
DR AlphaFoldDB; D1A2P3; -.
DR STRING; 471852.Tcur_2275; -.
DR KEGG; tcu:Tcur_2275; -.
DR eggNOG; COG0312; Bacteria.
DR HOGENOM; CLU_046126_0_0_11; -.
DR OrthoDB; 9763230at2; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43666:SF1; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR43666; TLDD PROTEIN; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ACY97841.1};
KW Protease {ECO:0000313|EMBL:ACY97841.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001918}.
FT DOMAIN 226..459
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 465 AA; 49325 MW; FFD25705E1D30EE2 CRC64;
MTPQESVERA LELSRADECV VIAEETSRAN LRWAGNTLTT NGVTRSRRLT VIALRHTAEG
VCSGVVSRSA VRDEQLEEVV RQAEQAAAES RPAEDAAPLA ADAPPGLGGE WAAPPAETDI
GVFARLAPAL GEAFAQAEAG GRRLYGFADH QMTSTYLGSS TGLRLRHDQP TGLMELNAKL
AGASGGGSAW TGVGTGDFTD VDVPALTDQL ARRLEWSRRR VELPAGRYET ILPPSAVADL
MIYLYWTAGA RDAHDGRTVF SAPGGGTRVG EKLAALPVTL SSDPAAPGLE CAPFVIARAS
GSDSSVFDNG LAVPATDWIS DGTLNALVQT RHSAALTGLP MTPAVDNLIL RGPDGAGASL
EDMVARTERG LLLTCLWYIR EVDPRTLLLT GLTRDGVYLV EGGEVVGEVN NFRFNESPVD
LLSRLTEVGA TARTLPREWS DYFTRAAMPP VRVADFNMST VSQAS
//
