ID D1AE49_THECD Unreviewed; 151 AA.
AC D1AE49;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=HNH endonuclease {ECO:0000313|EMBL:ACY99475.1};
GN OrderedLocusNames=Tcur_3946 {ECO:0000313|EMBL:ACY99475.1};
OS Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / KCTC
OS 9072 / NBRC 15933 / NCIMB 10081 / Henssen B9).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Thermomonospora.
OX NCBI_TaxID=471852 {ECO:0000313|EMBL:ACY99475.1, ECO:0000313|Proteomes:UP000001918};
RN [1] {ECO:0000313|EMBL:ACY99475.1, ECO:0000313|Proteomes:UP000001918}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19995 / DSM 43183 / JCM 3096 / KCTC 9072 / NBRC 15933 /
RC NCIMB 10081 / Henssen B9 {ECO:0000313|Proteomes:UP000001918};
RX PubMed=21475583; DOI=10.4056/sigs.1453580;
RA Chertkov O., Sikorski J., Nolan M., Lapidus A., Lucas S., Del Rio T.G.,
RA Tice H., Cheng J.F., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA Mavromatis K., Mikhailova N., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Djao O.D., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brettin T., Han C., Detter J.C., Rohde M., Goker M., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT "Complete genome sequence of Thermomonospora curvata type strain (B9).";
RL Stand. Genomic Sci. 1:13-22(2011).
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DR EMBL; CP001738; ACY99475.1; -; Genomic_DNA.
DR RefSeq; WP_012854259.1; NC_013510.1.
DR AlphaFoldDB; D1AE49; -.
DR STRING; 471852.Tcur_3946; -.
DR KEGG; tcu:Tcur_3946; -.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_1730544_0_0_11; -.
DR Proteomes; UP000001918; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR PANTHER; PTHR33877; SLL1193 PROTEIN; 1.
DR PANTHER; PTHR33877:SF1; TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMCRA; 1.
DR Pfam; PF01844; HNH; 1.
DR SMART; SM00507; HNHc; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:ACY99475.1};
KW Hydrolase {ECO:0000313|EMBL:ACY99475.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Nuclease {ECO:0000313|EMBL:ACY99475.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001918};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 109..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..66
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
SQ SEQUENCE 151 AA; 16159 MW; 0F4CBEC8DCDC3FD4 CRC64;
MSSKPNAARK RRIKRQLAAR DGAVCFYCGH PFGTLVEATI DHLVPKSKLP GWVQANLVLA
CHPCNKAKAD RLPQEFLRPC GFAPGLVPLG PPNAPTRNRR RVRHTAARLS AAVSAILPAT
LTAVLSAMWA GRLSAGTART VPGPVRHMSA T
//
