ID D1KE60_9GAMM Unreviewed; 397 AA.
AC D1KE60;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=2-polyprenyl-6-methoxyphenol hydroxylase {ECO:0000313|EMBL:EEZ79586.1};
GN ORFNames=Sup05_0908 {ECO:0000313|EMBL:EEZ79586.1};
OS uncultured Candidatus Thioglobus sp.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Candidatus Thioglobus;
OC environmental samples.
OX NCBI_TaxID=655186 {ECO:0000313|EMBL:EEZ79586.1, ECO:0000313|Proteomes:UP000009383};
RN [1] {ECO:0000313|EMBL:EEZ79586.1, ECO:0000313|Proteomes:UP000009383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=19900896; DOI=10.1126/science.1175309;
RA Walsh D.A., Zaikova E., Howes C.L., Song Y.C., Wright J.J., Tringe S.G.,
RA Tortell P.D., Hallam S.J.;
RT "Metagenome of a versatile chemolithoautotroph from expanding oceanic dead
RT zones.";
RL Science 326:578-582(2009).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the UbiH/COQ6 family.
CC {ECO:0000256|ARBA:ARBA00005349}.
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DR EMBL; GG730029; EEZ79586.1; -; Genomic_DNA.
DR AlphaFoldDB; D1KE60; -.
DR STRING; 655186.Sup05_0908; -.
DR PATRIC; fig|655186.3.peg.74; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000009383; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010971; UbiH/COQ6.
DR NCBIfam; TIGR01988; Ubi-OHases; 1.
DR PANTHER; PTHR43876:SF25; MONOOXYGENASE NMA2164-RELATED; 1.
DR PANTHER; PTHR43876; UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000009383}.
FT DOMAIN 3..304
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 397 AA; 44104 MW; 2D4236091E7B86DF CRC64;
MKYDIVIIGA GPAGLSFASS MMGLDVKVLV IERSSTDSIS NPKADGREIA LTHLSVKILK
KLGVWDLIDQ AQISPLKEAK VFDGDSPSLL NFKSDDSSIE ALGYLVPNYQ IRKALYERVI
QAKNITLLMD TTVEDVNPFE DYSEVLLSVD KKIEAKLVIA ADSRFSSIRR KMGIPSLMKD
FSKVMIVTKM KHERSHHNVA LECFDYGQTL ALLPMVGDAS SIILTVTTDK AQEVLNLSEE
KFNVKITQSF KGELGGMTQS GERYSYPLVA VHAQTFIANR FALIGDAAVG MHPVTAHGFN
LGLRGQDILA GLIKEAHQHG QDIGSKSLLK LFEKKHINLT RIMFFGTNGI VALFTNDAPY
VKQIRRLALK FAEHFPPIKY LITHHLTEAK KNRFLPF
//
