ID D1L8K8_PSECA Unreviewed; 169 AA.
AC D1L8K8;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=DNA topoisomerase (ATP-hydrolyzing) {ECO:0000256|ARBA:ARBA00012895};
DE EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE Flags: Fragment;
GN Name=gyrB {ECO:0000313|EMBL:ACY64544.1};
OS Pseudomonas cannabina.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=86840 {ECO:0000313|EMBL:ACY64544.1};
RN [1] {ECO:0000313|EMBL:ACY64544.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CFBP 2341 {ECO:0000313|EMBL:ACY64544.1};
RX PubMed=20227217; DOI=10.1016/j.syapm.2010.02.001;
RA Bull C.T., Manceau C., Lydon J., Kong H., Vinatzer B.A.,
RA Fischer-Le Saux M.;
RT "Pseudomonas cannabina pv. cannabina pv. nov., and Pseudomonas cannabina
RT pv. alisalensis (Cintas Koike and Bull, 2000) comb. nov., are members of
RT the emended species Pseudomonas cannabina (ex Sutic & Dowson 1959) Gardan,
RT Shafik, Belouin, Brosch, Grimont & Grimont 1999.";
RL Syst. Appl. Microbiol. 33:105-115(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP-dependent breakage, passage and rejoining of double-
CC stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC {ECO:0000256|ARBA:ARBA00010708}.
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DR EMBL; GQ859258; ACY64544.1; -; Genomic_DNA.
DR AlphaFoldDB; D1L8K8; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR000565; Topo_IIA_B.
DR InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR Pfam; PF00204; DNA_gyraseB; 1.
DR PRINTS; PR01159; DNAGYRASEB.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT DOMAIN 90..168
FT /note="DNA topoisomerase type IIA subunit B"
FT /evidence="ECO:0000259|Pfam:PF00204"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ACY64544.1"
FT NON_TER 169
FT /evidence="ECO:0000313|EMBL:ACY64544.1"
SQ SEQUENCE 169 AA; 19374 MW; 9C31B3B14C9DDB52 CRC64;
LLTVRRSGKI WEQTYVHGVP QEPMKIVGES DTTGTQIHFK PSADTFKNIH FSWDILAKRI
RELSFLNSGV GIVLKDERSG KEELFKYEGG LRAFVEYLNT NKTPVNEVFH FNVQRDDGIG
VEIALQWNDS FNENLLCFTN NIPQRDGGTH LVGFRSALTR NLNNYIEQE
//
