ID D1LXG5_SACKO Unreviewed; 463 AA.
AC D1LXG5;
DT 19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT 19-JAN-2010, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=TRAF-like protein {ECO:0000313|EMBL:ACY92671.1};
OS Saccoglossus kowalevskii (Acorn worm).
OC Eukaryota; Metazoa; Hemichordata; Enteropneusta; Harrimaniidae;
OC Saccoglossus.
OX NCBI_TaxID=10224 {ECO:0000313|EMBL:ACY92671.1};
RN [1] {ECO:0000313|EMBL:ACY92671.1}
RP NUCLEOTIDE SEQUENCE.
RA Freeman R.M.Jr., Wu M.M., Gerhart J.J.;
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; GU076142; ACY92671.1; -; mRNA.
DR RefSeq; NP_001161672.1; NM_001168200.1.
DR AlphaFoldDB; D1LXG5; -.
DR EnsemblMetazoa; NM_001168200.1; NP_001161672.1; LOC100313755.
DR GeneID; 100313755; -.
DR KEGG; sko:100313755; -.
DR OrthoDB; 2913784at2759; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd16641; mRING-HC-C3HC3D_TRAF4; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 4.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR012227; TNF_rcpt-assoc_TRAF_met.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR049342; TRAF_MEP1_MATH_dom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF144; TNF RECEPTOR-ASSOCIATED FACTOR 4; 1.
DR Pfam; PF21355; TRAF-mep_MATH; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR Pfam; PF02176; zf-TRAF; 2.
DR PIRSF; PIRSF015614; TRAF; 3.
DR SMART; SM00061; MATH; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 4.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50145; ZF_TRAF; 3.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 18..58
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 101..154
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 156..208
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 209..267
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT DOMAIN 307..455
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT ZN_FING 101..154
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 156..208
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT ZN_FING 209..267
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
SQ SEQUENCE 463 AA; 53621 MW; 40A086F1D0B49A94 CRC64;
MPGYQYKFAE KVRRKYVCPL CRLPMRDPVQ ITTCEHRFCD ICLQAYLSEG IFQCPEDKIP
LDYAKIYPDD DMTDEIVALT IRCSYYKDGC KWIDQLENLK SHLESCKYNQ VECPNNCTAV
ITRKLLKHHL SNECPRRTVV CEHCGADFTG VMMEGHRGSC QFQQVQCENK CGVKLQRRYL
SSHTLNECPK RMLSCKYCHK DVIFDTLQTH LHHCLKYPVT CPNRCDPERL ARGDLEKHLK
ENCPSSTINC PFQGQGCKYK SPRFALEQHL ENNSREHLLM MCMVAKRQEE EILSLRAELD
TMTGNTDGTL LWKIDNYSSL FAKAKKETTE LCSKPFFTSK YGYKLGLTAF LNGNGSGEGT
HFSLYIKILP GEYDTLLQWP FTHPVEFTLL DQTDDAKKRR HIKESFTADA SWKNFHRPSK
QNITLGYGYP TLISHEELNL RNYIRDDTIF IKVKVDTSKI VGI
//
