ID D1PLD0_9FIRM Unreviewed; 487 AA.
AC D1PLD0;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Coproporphyrinogen dehydrogenase HemZ {ECO:0000313|EMBL:EFB76788.1};
DE EC=1.3.99.22 {ECO:0000313|EMBL:EFB76788.1};
GN Name=hemZ {ECO:0000313|EMBL:EFB76788.1};
GN ORFNames=SUBVAR_05169 {ECO:0000313|EMBL:EFB76788.1};
OS Subdoligranulum variabile DSM 15176.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Subdoligranulum.
OX NCBI_TaxID=411471 {ECO:0000313|EMBL:EFB76788.1, ECO:0000313|Proteomes:UP000003438};
RN [1] {ECO:0000313|EMBL:EFB76788.1, ECO:0000313|Proteomes:UP000003438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15176 {ECO:0000313|EMBL:EFB76788.1,
RC ECO:0000313|Proteomes:UP000003438};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Nelson J., Hou S., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Nash W.E., Warren W., Chinwalla A.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFB76788.1}.
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DR EMBL; ACBY02000020; EFB76788.1; -; Genomic_DNA.
DR AlphaFoldDB; D1PLD0; -.
DR STRING; 411471.SUBVAR_05169; -.
DR eggNOG; COG0635; Bacteria.
DR HOGENOM; CLU_029256_0_0_9; -.
DR Proteomes; UP000003438; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR034505; Coproporphyrinogen-III_oxidase.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR023995; HemZ.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR NCBIfam; TIGR03994; rSAM_HemZ; 1.
DR PANTHER; PTHR13932; COPROPORPHYRINIGEN III OXIDASE; 1.
DR PANTHER; PTHR13932:SF1; OXYGEN-INDEPENDENT COPROPORPHYRINOGEN-III OXIDASE-LIKE PROTEIN HEMZ; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDF00310; oxygen-independent_coproporphy; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:EFB76788.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003438}.
FT DOMAIN 147..390
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 487 AA; 54369 MW; B48B47D714C790AA CRC64;
MMQIVLRGAA AGYEAEHTAR IFFPGAEKVT QIPESGDFVL AVSHEKTDFV LLRLGEALSW
RSALRAEDGD AEYTLCTLLF ELLREKTGQN PPWGMMTGVR PVRIIHDLRA MGATETEIED
RFLRHFACTP EKFTLARGIA DLQRPVLAGA DPMDCSVYAG IPFCPTRCSY CSFVSRTVGD
KATRALVQPY VDKLCEELTA IRQTADRCGL HIRTFYIGGG TPTSLSAAQL EQLMGHIART
FDLSTLDEYT VEAGRPDCTN AEKLRIIKQY GATRISINPQ TFSDEVLRNI GRRHTAQDII
DCFAAARAAG HQNINMDLIA GLPGDTVEGF THSLEQAIAL DPENITVHTL TLKRASNLVV
EHRAADYDDV AAMLARCDRL QQAGYRPYYL YRQKGTLQNL ENIGWAKPGK ECLYNIYIME
EIHTILSAGA GGSTKLVIPG KRHGKIERIF NFKYPTEYID RFAEILARKQ GVEDFYERCT
TQTICQP
//
