ID D1W0I9_9BACT Unreviewed; 468 AA.
AC D1W0I9;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Reverse transcriptase (RNA-dependent DNA polymerase) {ECO:0000313|EMBL:EFA97091.1};
GN ORFNames=HMPREF9019_1313 {ECO:0000313|EMBL:EFA97091.1};
OS Hoylesella timonensis CRIS 5C-B1.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=679189 {ECO:0000313|EMBL:EFA97091.1, ECO:0000313|Proteomes:UP000004001};
RN [1] {ECO:0000313|EMBL:EFA97091.1, ECO:0000313|Proteomes:UP000004001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIS 5C-B1 {ECO:0000313|EMBL:EFA97091.1,
RC ECO:0000313|Proteomes:UP000004001};
RA Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Strausberg R.L.,
RA Nelson K.E.;
RT "Genome Sequence of Prevotella timonensis CRIS 5C-B1.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the bacterial reverse transcriptase family.
CC {ECO:0000256|ARBA:ARBA00034120}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA97091.1}.
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DR EMBL; ADEF01000048; EFA97091.1; -; Genomic_DNA.
DR RefSeq; WP_008125103.1; NZ_ADEF01000048.1.
DR AlphaFoldDB; D1W0I9; -.
DR eggNOG; COG3344; Bacteria.
DR Proteomes; UP000004001; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd01651; RT_G2_intron; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR030931; Group_II_RT_mat.
DR InterPro; IPR013597; Mat_intron_G2.
DR InterPro; IPR000123; Reverse_transcriptase_msDNA.
DR InterPro; IPR000477; RT_dom.
DR NCBIfam; TIGR04416; group_II_RT_mat; 1.
DR PANTHER; PTHR34047:SF2; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR34047; NUCLEAR INTRON MATURASE 1, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF08388; GIIM; 1.
DR Pfam; PF00078; RVT_1; 1.
DR PRINTS; PR00866; RNADNAPOLMS.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW Nucleotidyltransferase {ECO:0000313|EMBL:EFA97091.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004001};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:EFA97091.1};
KW Transferase {ECO:0000313|EMBL:EFA97091.1}.
FT DOMAIN 95..321
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 54463 MW; F1E50C06768C0D17 CRC64;
MKERMQKTLS QVNGCPQRDR SETEWYGGVQ TFMWMCEDNI VEVPFDKEHL LEQILSPANL
NRAYKAVMRN KGCGGIDKMS CEQLLPWLLT NKDVLICSLI DGSYRPNPVK RVEIPKDNGK
MRLLGIPTVV DRLVQQAINQ VLTPIYENQF SKTSYGFRPR RGCHDALRGA QRIINEGYIY
VVDLDLERFF DTVSHSKLIE ILSRTIKDGR VVSLIHKYLR SGVMNKGLFE ASEEGTPQGG
PLSPLLSNIM LNELDKELER RGLPFVRYAD DSMIFCKSKR AAMRVKESIT RFIENTLYLK
VNKEKTVVSY VRGMKYLGYS FYVMKGKCQL TVHPKSKAKM KSKLKELTSR SNGWGYAKRK
QKLKEYIQGW VGYYHLANMK RFLLETDEWL RRRIRMCIWK AWKKVRTKVA NLIICGINQY
KAYEWGNTRK GYWRIADSPI LTRAIDNNRL RSAGYVTLMG AYLEWHPK
//
