ID D1W132_9BACT Unreviewed; 535 AA.
AC D1W132;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF9019_0551 {ECO:0000313|EMBL:EFA96940.1};
OS Hoylesella timonensis CRIS 5C-B1.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=679189 {ECO:0000313|EMBL:EFA96940.1, ECO:0000313|Proteomes:UP000004001};
RN [1] {ECO:0000313|EMBL:EFA96940.1, ECO:0000313|Proteomes:UP000004001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIS 5C-B1 {ECO:0000313|EMBL:EFA96940.1,
RC ECO:0000313|Proteomes:UP000004001};
RA Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Strausberg R.L.,
RA Nelson K.E.;
RT "Genome Sequence of Prevotella timonensis CRIS 5C-B1.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA96940.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADEF01000049; EFA96940.1; -; Genomic_DNA.
DR AlphaFoldDB; D1W132; -.
DR eggNOG; COG3525; Bacteria.
DR Proteomes; UP000004001; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFA96940.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004001}.
FT DOMAIN 17..145
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 149..491
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 323
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 535 AA; 61287 MW; EE1424556881EF7A CRC64;
MLLTTLFLQS YAGIANYEVV PLPQSIKLVK GQGFNLTDGT LIVYAGADEA MQRNAQFLAQ
YFKSMTNKEV SVTNDRRAKN GCIVLALDKK LKGDEAYHIS VSNKTIRVTG KTPKGVFYGI
QTLRKSLAEE IHQDAIVFPA VEIDDEPRFG YRGMMLDCAR HFFPVSFVKK FIDLLALHNM
NTFHWHLTDD QGWRIEIKKY PELTKIGSVR QRTVIGRDSD LDDGTPYGGY YTQEEAREIV
EYARQRHIKV IPEIDMPGHM MAALATFPEL GCTGGPYEVG FGWGIYLDVL CLGNEKIYPF
LEDIIDELVP IFPAKEFHIG GDETPRDYWK VCPKCQALAK REGIDTHQLQ AYFTKRMEKY
LNSKGKIIIG WDEILEGDIN PSATIMSWRG VSNGNKASAD GHDVIMSPTE FAYFDYYQTD
QTRNEPMAWG GCLPVEKVYS FDPAPDSLSA KAKQHIIGAQ ANLWTEYIPY TQQAEYMLLP
RMAAMAEVQW MPVSQKNYQA FVKRLYRLAK VYDHEGYIYA LHLWPERYHF NRNRW
//
