ID D1W187_9BACT Unreviewed; 563 AA.
AC D1W187;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=TrkA C-terminal domain protein {ECO:0000313|EMBL:EFA96893.1};
GN Name=trkA {ECO:0000313|EMBL:EFA96893.1};
GN ORFNames=HMPREF9019_0861 {ECO:0000313|EMBL:EFA96893.1};
OS Hoylesella timonensis CRIS 5C-B1.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Hoylesella.
OX NCBI_TaxID=679189 {ECO:0000313|EMBL:EFA96893.1, ECO:0000313|Proteomes:UP000004001};
RN [1] {ECO:0000313|EMBL:EFA96893.1, ECO:0000313|Proteomes:UP000004001}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CRIS 5C-B1 {ECO:0000313|EMBL:EFA96893.1,
RC ECO:0000313|Proteomes:UP000004001};
RA Durkin A.S., Madupu R., Torralba M., Methe B., Sutton G., Strausberg R.L.,
RA Nelson K.E.;
RT "Genome Sequence of Prevotella timonensis CRIS 5C-B1.";
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC {ECO:0000256|ARBA:ARBA00009854}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFA96893.1}.
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DR EMBL; ADEF01000055; EFA96893.1; -; Genomic_DNA.
DR RefSeq; WP_008125365.1; NZ_ADEF01000055.1.
DR AlphaFoldDB; D1W187; -.
DR eggNOG; COG0569; Bacteria.
DR eggNOG; COG2985; Bacteria.
DR Proteomes; UP000004001; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR006512; YidE_YbjL.
DR NCBIfam; TIGR01625; YidE_YbjL_dupl; 2.
DR PANTHER; PTHR30445:SF3; TRANSPORT PROTEIN YIDE-RELATED; 1.
DR PANTHER; PTHR30445; UNCHARACTERIZED; 1.
DR Pfam; PF06826; Asp-Al_Ex; 2.
DR Pfam; PF02080; TrkA_C; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004001};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 13..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..500
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 201..287
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 291..374
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 563 AA; 60924 MW; 86D7F535B1A7EFD3 CRC64;
MDWIISLFTN NDSVAHIALL YAIVIAVGVL LGKIKVGGVS LGVTFVLFAG IVAGHVGFTG
PTNILTFVQD FGLILFVFCI GLQVGPGFFE SFKRGGVTLN LLSTALILLN IAVMFACYYI
FFDTSDSHNL PMMVGTLYGA VTNTPGLGAA NEALTAIFTK EDMPQIANGY ACAYPLGVLG
IIGATIAIRY ICRVNLEKED DDLAQAEGDN PNAKPCQIRL KVSNAYIAGR SLQQIKEFLN
RDFVCTRLLH EDNLEIPREE TVIQKDDELL IVCAEADAEA VQAFIGPTID LPWEEEDTKQ
PMISRRIVIT NSSMNGKILG KMHFASVYGV NITRITRQGI DLFASQNLHL HVGDRVMVVG
PEENVERVAD VMGNSVKHLN VPNIATIFIG VFIGIIFGSI PISIPGMPVP LKLGIAGGPL
IIAILIGRYG YKMKLVTYTT TSANMMLREI GLVLFLASVG IKAGASFVET VVEGDGLKYV
YTGVLITVIP ILIIGTIARL KYKFNYFTIM GMLAGTCTDP PALAYANSVC SHEAPSIGYS
TVYPLSMFLR IFTAQMIVLF CCG
//
