ID D1Y7K8_9BACT Unreviewed; 577 AA.
AC D1Y7K8;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Hydrogenase, Fe-only {ECO:0000313|EMBL:EFB89727.1};
DE EC=1.12.-.- {ECO:0000313|EMBL:EFB89727.1};
GN ORFNames=HMPREF7215_1336 {ECO:0000313|EMBL:EFB89727.1};
OS Pyramidobacter piscolens W5455.
OC Bacteria; Synergistota; Synergistia; Synergistales;
OC Dethiosulfovibrionaceae; Pyramidobacter.
OX NCBI_TaxID=352165 {ECO:0000313|EMBL:EFB89727.1, ECO:0000313|Proteomes:UP000006462};
RN [1] {ECO:0000313|EMBL:EFB89727.1, ECO:0000313|Proteomes:UP000006462}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W5455 {ECO:0000313|EMBL:EFB89727.1,
RC ECO:0000313|Proteomes:UP000006462};
RA Shrivastava S., Madupu R., Durkin A.S., Torralba M., Methe B., Sutton G.G.,
RA Strausberg R.L., Nelson K.E.;
RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFB89727.1}.
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DR EMBL; ADFP01000122; EFB89727.1; -; Genomic_DNA.
DR RefSeq; WP_009165839.1; NZ_ADFP01000122.1.
DR AlphaFoldDB; D1Y7K8; -.
DR STRING; 352165.HMPREF7215_1336; -.
DR eggNOG; COG3383; Bacteria.
DR eggNOG; COG4624; Bacteria.
DR OrthoDB; 9805142at2; -.
DR Proteomes; UP000006462; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.740; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.1780; -; 1.
DR Gene3D; 4.10.260.20; Iron hydrogenase, small subunit; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR009016; Fe_hydrogenase.
DR InterPro; IPR004108; Fe_hydrogenase_lsu_C.
DR InterPro; IPR003149; Fe_hydrogenase_ssu.
DR InterPro; IPR036991; Fe_hydrogenase_ssu_sf.
DR InterPro; IPR013352; Fe_hydrogenase_subset.
DR InterPro; IPR019574; NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd.
DR NCBIfam; TIGR02512; FeFe_hydrog_A; 1.
DR NCBIfam; NF040763; FeFe_hydrog_A6; 1.
DR PANTHER; PTHR11615:SF345; CATALYTIC SUBUNIT OF IRON-ONLY HYDROGENASE-RELATED; 1.
DR PANTHER; PTHR11615; NITRATE, FORMATE, IRON DEHYDROGENASE; 1.
DR Pfam; PF02906; Fe_hyd_lg_C; 1.
DR Pfam; PF02256; Fe_hyd_SSU; 1.
DR Pfam; PF13510; Fer2_4; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF10588; NADH-G_4Fe-4S_3; 1.
DR SMART; SM00902; Fe_hyd_SSU; 1.
DR SMART; SM00929; NADH-G_4Fe-4S_3; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF53920; Fe-only hydrogenase; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
DR PROSITE; PS51839; 4FE4S_HC3; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:EFB89727.1}.
FT DOMAIN 1..78
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 78..117
FT /note="4Fe-4S His(Cys)3-ligated-type"
FT /evidence="ECO:0000259|PROSITE:PS51839"
FT DOMAIN 136..166
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 179..208
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 577 AA; 63367 MW; 62E566A48FD4AC2C CRC64;
MVNVVIDGKR IKVPERTTIL DAAKAAGIRI PTLCFLEGVN EIGACRVCVV EVEGHERLFT
ACNNPVEESM VIHTNSKKAR EARRANVRMI LSEHDDHCPS CVRSGNCELQ RIANELNIHD
TPFEKHYVSR RTSPDFPLIR DFSLCIKCMR CVQVCDKIQH ANVWDVVNTG AKTTVDVARV
YRLEDADCAL CGQCITHCPV GALHERDDTQ KVLDAIDDPE KIVLVQIAPA IRTAWGEEFG
MKPGEATVTR LAAALRLVGF DYVFDTNFSA DLTIMEEGSE FVERLKHRDR EKFPMFTSCC
PGWIRFVKSH WPQFVGQLSS AKSPQQMFGA VAKSWYAQTL GVDPSRIFSV SIMPCLAKKA
ECALPGMDGA GAGQDVDVAL TTREVSRLIR SLQIQPQDLA DEELDMPLGV GSGAGAIFGA
TGGVMEAALR SAFFLVTGKN PEPDAFKSVR GMDGWKEATF DIAGTALKVA VVNGLGNADK
LLAALDRGDV RYDFVEVMAC PGGCVGGGGQ PIHDRVEMAP QRAPTLYDID RGMELRFSHE
NPSILACYQQ FLGAPLSEKA HRLLHTTYHG WKMPGEK
//
