ID   D1YYG3_METPS            Unreviewed;       545 AA.
AC   D1YYG3;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   OrderedLocusNames=MCP_1413 {ECO:0000313|EMBL:BAI61485.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI61485.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; AP011532; BAI61485.1; -; Genomic_DNA.
DR   AlphaFoldDB; D1YYG3; -.
DR   STRING; 304371.MCP_1413; -.
DR   KEGG; mpd:MCP_1413; -.
DR   eggNOG; arCOG02353; Archaea.
DR   eggNOG; arCOG06192; Archaea.
DR   eggNOG; arCOG06515; Archaea.
DR   InParanoid; D1YYG3; -.
DR   OrthoDB; 8127at2157; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00075; HATPase; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF00989; PAS; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:BAI61485.1};
KW   Transferase {ECO:0000313|EMBL:BAI61485.1}.
FT   DOMAIN          190..256
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          264..314
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          325..545
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
FT   COILED          173..200
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   545 AA;  62294 MW;  DB9B7A8AB990501A CRC64;
     MRGILIHTDI KIGDRPETFY HSILDSLTSN IAILNDSGII IDINDSWDRF ALQNGIKSLD
     KVGVGVSYFE VCRKAHGEHS DEAPVALDGL LSVLKGNISY FELEYPCDSP DKKRWFLMRA
     TRFMENSRKY LVVTHIDITR RKMAETELLA SYKELETRYK AQAEISKDYG DMCKESIIEK
     KRLEEALRKS EKKFQNLLER APFAIYIYRG EKNCCYVNPA AEALTGYTRD EFINMSYWDI
     AHPDYRELVK ERGIKRQKGV TVPARYQIKI ITKSGDGRWI DINAANIMFE RKPAVLVTMI
     DITEQKLAEE TLSEARAQAE VYIDLMSHDI NNMNQIAMGS LELFLDRSQT GKKIEGEDLK
     LLRSSYLTLQ SISRLIDNVR KIQSLKSGMI RPEVVDTGLM IAEVIKAYEN IPGRDVKIHY
     TPVFGYMVKA CELFQDVIVN IIDNAIKHST GPLLINIEDA EVIEDGKKYY RIFIEDNGPG
     IPDEKKKDIF ERYKRGDTKA RGRGLGLYLV KTLIDDFGGK VWAEDRVPGE YGKGSKFVIM
     LPAIT
//