ID D2A8Q6_SHIF2 Unreviewed; 308 AA.
AC D2A8Q6;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=HTH-type transcriptional activator AllS {ECO:0000256|ARBA:ARBA00040468};
GN Name=allS {ECO:0000313|EMBL:ADA72822.1};
GN OrderedLocusNames=SFxv_0489 {ECO:0000313|EMBL:ADA72822.1};
OS Shigella flexneri serotype X (strain 2002017).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=591020 {ECO:0000313|EMBL:ADA72822.1, ECO:0000313|Proteomes:UP000001884};
RN [1] {ECO:0000313|EMBL:ADA72822.1, ECO:0000313|Proteomes:UP000001884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2002017 {ECO:0000313|EMBL:ADA72822.1,
RC ECO:0000313|Proteomes:UP000001884};
RX PubMed=19955273; DOI=10.1128/JCM.00614-09;
RA Ye C., Lan R., Xia S., Zhang J., Sun Q., Zhang S., Jing H., Wang L., Li Z.,
RA Zhou Z., Zhao A., Cui Z., Cao J., Jin D., Huang L., Wang Y., Luo X.,
RA Bai X., Wang Y., Wang P., Xu Q., Xu J.;
RT "Emergence of a new multidrug-resistant serotype X variant in an epidemic
RT clone of Shigella flexneri.";
RL J. Clin. Microbiol. 48:419-426(2010).
CC -!- FUNCTION: Positive regulator essential for the expression of allD
CC operon. Binds to the allD promoter. {ECO:0000256|ARBA:ARBA00037302}.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP001383; ADA72822.1; -; Genomic_DNA.
DR RefSeq; WP_000460136.1; NC_017328.1.
DR AlphaFoldDB; D2A8Q6; -.
DR KEGG; sfe:SFxv_0489; -.
DR PATRIC; fig|591020.3.peg.516; -.
DR HOGENOM; CLU_039613_35_1_6; -.
DR Proteomes; UP000001884; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30579:SF0; HTH-TYPE TRANSCRIPTIONAL ACTIVATOR ALLS; 1.
DR PANTHER; PTHR30579; TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
FT DOMAIN 2..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 308 AA; 34427 MW; 436F126AE788B1E3 CRC64;
MFDPETLRTF IAVAETGSFS KAAERLCKTT ATISYRIKLL EENTGVALFF RTTRSVTLTA
AGEHLLSQAR DWLSWLESMP SELQQVNDGV ERQVNIVINN LLYNPQAVAQ LLAWLNERYP
FTQFHISRQI YMGVWDSLLY EGFSLAIGVT GTEALANTFS LDPLGSVQWR FVMAADHPLA
NVEEPLTEAQ LRRFPAVNIE DSAGTLTKRV AWRLPGQKEI IVPDMETKIA AHLAGVGIGF
LPKSLCQSMI DNQQLVSRVI PTMRPPSPLS LAWRKFGSCK AVEDIVTLFT QHRPEISGFL
EIFGTPRS
//
