ID D2AAF6_SHIF2 Unreviewed; 282 AA.
AC D2AAF6;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=HTH-type transcriptional regulator yiaJ {ECO:0000313|EMBL:ADA75923.1};
GN Name=yiaJ {ECO:0000313|EMBL:ADA75923.1};
GN OrderedLocusNames=SFxv_3942 {ECO:0000313|EMBL:ADA75923.1};
OS Shigella flexneri serotype X (strain 2002017).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=591020 {ECO:0000313|EMBL:ADA75923.1, ECO:0000313|Proteomes:UP000001884};
RN [1] {ECO:0000313|EMBL:ADA75923.1, ECO:0000313|Proteomes:UP000001884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2002017 {ECO:0000313|EMBL:ADA75923.1,
RC ECO:0000313|Proteomes:UP000001884};
RX PubMed=19955273; DOI=10.1128/JCM.00614-09;
RA Ye C., Lan R., Xia S., Zhang J., Sun Q., Zhang S., Jing H., Wang L., Li Z.,
RA Zhou Z., Zhao A., Cui Z., Cao J., Jin D., Huang L., Wang Y., Luo X.,
RA Bai X., Wang Y., Wang P., Xu Q., Xu J.;
RT "Emergence of a new multidrug-resistant serotype X variant in an epidemic
RT clone of Shigella flexneri.";
RL J. Clin. Microbiol. 48:419-426(2010).
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DR EMBL; CP001383; ADA75923.1; -; Genomic_DNA.
DR RefSeq; WP_000514227.1; NC_017328.1.
DR AlphaFoldDB; D2AAF6; -.
DR KEGG; sfe:SFxv_3942; -.
DR PATRIC; fig|591020.3.peg.4236; -.
DR HOGENOM; CLU_062618_5_5_6; -.
DR Proteomes; UP000001884; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136:SF19; DNA-BINDING TRANSCRIPTIONAL REPRESSOR YIAJ; 1.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 23..85
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 86..272
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 282 AA; 31041 MW; 25005C595A890423 CRC64;
MGKEVMGKKE NEMAQEKERP AGSQSLFRGL MLIEILSNYP NGCPLAHLSE LAGLNKSTVH
RLLQGLQSCG YVTTAPAAGS YRLTTKFIAV GQKALSSLNI IHIAAPHLEA LNIATGETIN
FSSREDDHAI LIYKLEPTTG MLRTCAYIGQ HMPLYCSAMG KIYMAFGHPD YVKSYWENHQ
HEIQPLTRNT ITELPAMFDE LAHIRESGAA MDREENELGV SCIAVPVFDI HGRVPYAVSI
SLSTSRLKQV GEKNLLKPLR ETAQAISNEL GFTVRDDLGA IT
//
