ID D2AIA9_SHIF2 Unreviewed; 550 AA.
AC D2AIA9;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE RecName: Full=Flagellin {ECO:0000256|RuleBase:RU362073};
GN Name=fliC {ECO:0000313|EMBL:ADA74348.1};
GN OrderedLocusNames=SFxv_2195 {ECO:0000313|EMBL:ADA74348.1};
OS Shigella flexneri serotype X (strain 2002017).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=591020 {ECO:0000313|EMBL:ADA74348.1, ECO:0000313|Proteomes:UP000001884};
RN [1] {ECO:0000313|EMBL:ADA74348.1, ECO:0000313|Proteomes:UP000001884}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2002017 {ECO:0000313|EMBL:ADA74348.1,
RC ECO:0000313|Proteomes:UP000001884};
RX PubMed=19955273; DOI=10.1128/JCM.00614-09;
RA Ye C., Lan R., Xia S., Zhang J., Sun Q., Zhang S., Jing H., Wang L., Li Z.,
RA Zhou Z., Zhao A., Cui Z., Cao J., Jin D., Huang L., Wang Y., Luo X.,
RA Bai X., Wang Y., Wang P., Xu Q., Xu J.;
RT "Emergence of a new multidrug-resistant serotype X variant in an epidemic
RT clone of Shigella flexneri.";
RL J. Clin. Microbiol. 48:419-426(2010).
CC -!- FUNCTION: Flagellin is the subunit protein which polymerizes to form
CC the filaments of bacterial flagella. {ECO:0000256|ARBA:ARBA00002270,
CC ECO:0000256|RuleBase:RU362073}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362073}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362073}.
CC -!- SIMILARITY: Belongs to the bacterial flagellin family.
CC {ECO:0000256|ARBA:ARBA00005709, ECO:0000256|RuleBase:RU362073}.
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DR EMBL; CP001383; ADA74348.1; -; Genomic_DNA.
DR RefSeq; WP_000079690.1; NC_017328.1.
DR AlphaFoldDB; D2AIA9; -.
DR SMR; D2AIA9; -.
DR KEGG; sfe:SFxv_2195; -.
DR PATRIC; fig|591020.3.peg.2375; -.
DR HOGENOM; CLU_011142_7_2_6; -.
DR Proteomes; UP000001884; Chromosome.
DR GO; GO:0009288; C:bacterial-type flagellum; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.280.190; -; 1.
DR Gene3D; 2.30.220.10; f41 fragment of flagellin, C-terminal domain; 1.
DR Gene3D; 2.170.280.10; f41 fragment of flagellin, middle domain; 1.
DR Gene3D; 1.20.1330.10; f41 fragment of flagellin, N-terminal domain; 1.
DR Gene3D; 6.10.10.10; Flagellar export chaperone, C-terminal domain; 1.
DR InterPro; IPR001492; Flagellin.
DR InterPro; IPR046358; Flagellin_C.
DR InterPro; IPR042187; Flagellin_C_sub2.
DR InterPro; IPR001029; Flagellin_N.
DR InterPro; IPR032826; FliC_H7.
DR PANTHER; PTHR42792; FLAGELLIN; 1.
DR PANTHER; PTHR42792:SF2; FLAGELLIN; 1.
DR Pfam; PF00700; Flagellin_C; 1.
DR Pfam; PF00669; Flagellin_N; 1.
DR Pfam; PF12445; FliC; 1.
DR PRINTS; PR00207; FLAGELLIN.
DR SUPFAM; SSF64518; Phase 1 flagellin; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362073};
KW Cell projection {ECO:0000313|EMBL:ADA74348.1};
KW Cilium {ECO:0000313|EMBL:ADA74348.1};
KW Flagellum {ECO:0000313|EMBL:ADA74348.1};
KW Secreted {ECO:0000256|RuleBase:RU362073}.
FT DOMAIN 5..140
FT /note="Flagellin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00669"
FT DOMAIN 330..454
FT /note="Flagellin H7-serospecific"
FT /evidence="ECO:0000259|Pfam:PF12445"
FT DOMAIN 463..548
FT /note="Flagellin C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00700"
SQ SEQUENCE 550 AA; 56637 MW; CC921C9A8EF200B6 CRC64;
MAQVINTNSL SLITQNNINK NQSALSSSIE RLSSGLRINS AKDDAAGQAI ANRFTSNIKG
LTQAARNAND GISVAQTTEG ALSEINNNLQ RIRELTVQAS TGTNSDSDLD SIQDEIKSRL
DEIDRVSGQT QFNGVNVLAK DGSMKIQVGA NDGQTITIDL KKIDSDTLGL NGFNVNGGGA
VANTAASKAD LVAANATVVG NKYTVSAGYD AAKASDLLAG VSDGDTVQAT INNGFGTAAS
ATNYKYDSAS KSYSFDTTTA SAADVQKYLT PGVGDTAKGT ITIDGSAQDV QISSDGKITA
SNGDKLYIDT TGRLTKNGSG ASLTEASLST LAANNTKATT IDIGGTSISF TGNSTTPDTI
TYSVTGAKVD QAAFDKAVST SGNNVDFTTA GYSVNGTTGA VTKGVDSVYV DNNEALTTSD
TVDFYLQDDG SVTNGSGKAV YKDADGKLTT DAETKAATTA DPLKALDEAI SSIDKFRSSL
GAVQNRLDSA VTNLNNTTTN LSEAQSRIQD ADYATEVSNM SKAQIIQQAG NSVLAKANQV
PQQVLSLLQG
//
