ID   D2B2B4_STRRD            Unreviewed;       481 AA.
AC   D2B2B4;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:ACZ91140.1};
GN   OrderedLocusNames=Sros_8497 {ECO:0000313|EMBL:ACZ91140.1};
OS   Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS   9100).
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Streptosporangiaceae; Streptosporangium.
OX   NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ91140.1, ECO:0000313|Proteomes:UP000002029};
RN   [1] {ECO:0000313|EMBL:ACZ91140.1, ECO:0000313|Proteomes:UP000002029}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC   {ECO:0000313|Proteomes:UP000002029};
RX   PubMed=21304675; DOI=10.4056/sigs.631049;
RA   Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA   Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA   Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA   Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA   Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Streptosporangium roseum type strain (NI
RT   9100).";
RL   Stand. Genomic Sci. 2:29-37(2010).
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family.
CC       {ECO:0000256|ARBA:ARBA00005384}.
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DR   EMBL; CP001814; ACZ91140.1; -; Genomic_DNA.
DR   RefSeq; WP_012894869.1; NC_013595.1.
DR   AlphaFoldDB; D2B2B4; -.
DR   STRING; 479432.Sros_8497; -.
DR   KEGG; sro:Sros_8497; -.
DR   eggNOG; COG1167; Bacteria.
DR   HOGENOM; CLU_017584_0_1_11; -.
DR   Proteomes; UP000002029; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   PRINTS; PR00035; HTHGNTR.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002029};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          13..81
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   481 AA;  50752 MW;  1638F173A4A07D57 CRC64;
     MADLHLVVDR AAGGIAGQIA RELREAVRQG RLPAGGRLPA SRELARDLGL SRGVVVEAYE
     QLVAEGLLIS RVGAGTSVAP AASRPPGAAL RDPLVPAFEP YYGHRSTSPD LSAFPRERWL
     ASIRRALATL PADALDYGDP GGVPALREEL ADYLRRVRAA DAGPDDIVIV GGVAQGLSLT
     VQALAGQLPE GRAGHDLNWF VDRLAHPVPP PGRIRLAVED PAGVRQLPLL RAAGADLVAV
     PVDREGIDVG ALAATGARAV LLTPAHQYPT GVVLSPRRRA ELIEWAAGTG ATILEDDYDA
     EFRFDRDPVG CLQGLAPGRV VLAGSVSKSL APGLRLGWVV APPGIAESVR RARGELDLGS
     PVLEQYALAD LIGNGGYDRH LRRMRREYRA RRDAFVRALA EHLPEIRVHG VSAGLHLFAE
     LPGGCDESQA TEAAQACGLA AEPVGAMRGT PGPPALVMGF ARLPVHRADQ AIRAFAAGLR
     R
//