ID D2B8Q8_STRRD Unreviewed; 511 AA.
AC D2B8Q8;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ACZ87868.1};
GN OrderedLocusNames=Sros_5079 {ECO:0000313|EMBL:ACZ87868.1};
OS Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS 9100).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Streptosporangium.
OX NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ87868.1, ECO:0000313|Proteomes:UP000002029};
RN [1] {ECO:0000313|EMBL:ACZ87868.1, ECO:0000313|Proteomes:UP000002029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC {ECO:0000313|Proteomes:UP000002029};
RX PubMed=21304675; DOI=10.4056/sigs.631049;
RA Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Streptosporangium roseum type strain (NI
RT 9100).";
RL Stand. Genomic Sci. 2:29-37(2010).
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DR EMBL; CP001814; ACZ87868.1; -; Genomic_DNA.
DR RefSeq; WP_012891605.1; NC_013595.1.
DR AlphaFoldDB; D2B8Q8; -.
DR STRING; 479432.Sros_5079; -.
DR KEGG; sro:Sros_5079; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_7_11; -.
DR OrthoDB; 4363623at2; -.
DR Proteomes; UP000002029; Chromosome.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ACZ87868.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002029}.
FT DOMAIN 8..379
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 429..504
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 511 AA; 55754 MW; E86F4BED8B9FFEA3 CRC64;
MLNLSIILED SARNTPDRTA LVFGDLRLPY SMVDSVANQV ANLLVARGIG KGDKVALLCP
NLPYFPFVYF GILKAGATVV PLNVLLQPRE ITYHLTDSDT KALFCFEGSP ELPMGARGRE
AFDAAEGCEL FFVLPATPLA TESEYGESFW AALDGMSGEF ETVQTEPDDT AAILYTSGTT
GRPKGAVLTH MNMLTNTIVS DEMFPADPRG DVSLAVLPLF HSFGQTAVMN VSVRRRATLV
LQPRFESGET LKLMREEKVT MFAGVPTMFW ALLSKIHADG DEAPSTLRVA VAGGAACPVE
VLKDFEGTFG IPILEGYGLS ETSPVASFNQ LGRPTKPGTI GFPVWGVQMR LVDDGWNTIE
GEGSGEIAIR GHNVMKGYYG RPEATEEVMR DGWFRTGDIA TCDEDGYYTI IDRTKDMIIR
GGFNVYPREL EEVLMTHPAV SLVAVVGVPH DSHGEEIKAY VIPAPGATAS ESELIAWCKA
NMAAYKYPRI VEFRENLPMT ATGKILKREL R
//
