ID D2BES5_STRRD Unreviewed; 681 AA.
AC D2BES5;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Acetyl-CoA synthetase {ECO:0000313|EMBL:ACZ84438.1};
GN OrderedLocusNames=Sros_1444 {ECO:0000313|EMBL:ACZ84438.1};
OS Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI
OS 9100).
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Streptosporangium.
OX NCBI_TaxID=479432 {ECO:0000313|EMBL:ACZ84438.1, ECO:0000313|Proteomes:UP000002029};
RN [1] {ECO:0000313|EMBL:ACZ84438.1, ECO:0000313|Proteomes:UP000002029}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100
RC {ECO:0000313|Proteomes:UP000002029};
RX PubMed=21304675; DOI=10.4056/sigs.631049;
RA Nolan M., Sikorski J., Jando M., Lucas S., Lapidus A., Glavina Del Rio T.,
RA Chen F., Tice H., Pitluck S., Cheng J.F., Chertkov O., Sims D., Meincke L.,
RA Brettin T., Han C., Detter J.C., Bruce D., Goodwin L., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Ivanova N., Mavromatis K., Mikhailova N.,
RA Chen A., Palaniappan K., Chain P., Rohde M., Goker M., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Streptosporangium roseum type strain (NI
RT 9100).";
RL Stand. Genomic Sci. 2:29-37(2010).
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DR EMBL; CP001814; ACZ84438.1; -; Genomic_DNA.
DR RefSeq; WP_012888183.1; NC_013595.1.
DR AlphaFoldDB; D2BES5; -.
DR STRING; 479432.Sros_1444; -.
DR KEGG; sro:Sros_1444; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_3_3_11; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000002029; Chromosome.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002029}.
FT DOMAIN 34..89
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 91..501
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT REGION 229..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 681 AA; 72202 MW; 1366E4162988F3CD CRC64;
MVEEGALLWE PAPEVVRDAK VTRYMKWLGR PGDYESLWQW SVDAPAEFWT SVWDYFGVVG
ERGDGPVISG TMPGAEWFTG STLNYAANAL RRAGNDPDRL AVVFRDEAGG RRTLTLGELA
EEVARVRTGL AGLGVGRGDR VAAYAPNIPE TLVAFLATAS LGAIWSSCSP DFGAPSVIDR
FTQIEPKVLI AVDGYDYNGK RFDRAEVVRD IAAKLPTLVA QVRIATPYGP GTPGADGASG
TGSPSGGPDE PGTEGTSGGS GAPGAGRAPS EGGTTILGWA DLRDSAGPLA FEPVPFGHPL
WIVYSSGTTG LPKPIVHGHG GVVLEHLKAL SFHQDLGEDD VFFWYTTTGW MMWNYLIGGL
LVGSTVVLYD GAATYPGTDA LWRLAAEEGV TYFGTGAPYL VASMKAGLRP AGLTALRGLG
STGSPLPPEG FAWVHDALPE VQLGSFSGGT DVCTGFVGAV PLLPVRAGVI PCRCLGARVE
SFDSSGAPVV GEVGELVLTA PMPSMPVMFW NDADGSRYRE SYFADYPGVW RHGDWIKILP
DGGCVIYGRS DSTLNRGGVR MGTSEFYRVV ERFDEIADSL VIDTGQLGQE GRLLLYVTMA
EGAALSDALV TDLRAALRDA LSPRHVPNEI IEVPGIPRTL SGKKLEVPVR KILLGVPPEK
AANLDAMANP EVLSYFAPVK D
//
