ID   D2EC21_SPAJD            Unreviewed;       306 AA.
AC   D2EC21;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   SubName: Full=Diabetes-related ankyrin repeat protein {ECO:0000313|EMBL:CBI62582.1};
GN   Name=darp {ECO:0000313|EMBL:CBI62582.1};
OS   Spalax judaei (Judean Mountains blind mole rat) (Nannospalax judaei).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Spalacidae; Spalacinae; Nannospalax.
OX   NCBI_TaxID=134510 {ECO:0000313|EMBL:CBI62582.1};
RN   [1] {ECO:0000313|EMBL:CBI62582.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Neck skeletal muscle {ECO:0000313|EMBL:CBI62582.1};
RX   PubMed=19967343; DOI=10.1007/s00239-009-9306-6;
RA   Band M., Joel A., Avivi A.;
RT   "The Muscle Ankyrin Repeat Proteins Are Hypoxia-Sensitive: In Vivo mRNA
RT   Expression in the Hypoxia-Tolerant Blind Subterranean Mole Rat, Spalax
RT   ehrenbergi.";
RL   J. Mol. Evol. 70:1-12(2010).
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DR   EMBL; FN598563; CBI62582.1; -; mRNA.
DR   AlphaFoldDB; D2EC21; -.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR24193:SF122; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 23; 1.
DR   PANTHER; PTHR24193; ANKYRIN REPEAT PROTEIN; 1.
DR   Pfam; PF12796; Ank_2; 2.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 4.
DR   PROSITE; PS50088; ANK_REPEAT; 4.
PE   2: Evidence at transcript level;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}.
FT   REPEAT          144..176
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          177..209
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          210..242
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          243..275
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ   SEQUENCE   306 AA;  34589 MW;  807006F21782B9E0 CRC64;
     MDFISIQQLV SGERVDRKVL GFGHGIPDPG GWPSDWRLGP QEAVAREKLK LEEEKKKKLE
     RFNSSRLNLD NLTDLENLIQ RRREKRLRCK VPPREPEPVV ELQPQFRMDP VDLELFLKAA
     AENQEALIDK YLTDGGDPNA HDKLHRTALH WACLKGHEQL VNKLLVAGAA AEAQDLLDRT
     PLFWACRGGH LDILKQLLNQ GAQVNARDKI WSTPLHVAVR TGHSDCLEHL IECGAHIDAQ
     DKEGDTALHE AVRHGHYKAM KLLLLYGAKL GMKNVASLTP VQLARDWQRG IREALQAHVG
     HPRTRC
//