ID D2GU16_AILME Unreviewed; 960 AA.
AC D2GU16;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 13-SEP-2023, entry version 54.
DE RecName: Full=Seizure related 6 homolog {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PANDA_000097 {ECO:0000313|EMBL:EFB26117.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB26117.1};
RN [1] {ECO:0000313|EMBL:EFB26117.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; GL192339; EFB26117.1; -; Genomic_DNA.
DR AlphaFoldDB; D2GU16; -.
DR InParanoid; D2GU16; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00033; CCP; 5.
DR CDD; cd00041; CUB; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 5.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 2.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR45656; PROTEIN CBR-CLEC-78; 1.
DR PANTHER; PTHR45656:SF1; SEIZURE PROTEIN 6 HOMOLOG; 1.
DR Pfam; PF00431; CUB; 2.
DR Pfam; PF00084; Sushi; 5.
DR SMART; SM00032; CCP; 5.
DR SMART; SM00042; CUB; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 5.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 3.
DR PROSITE; PS01180; CUB; 2.
DR PROSITE; PS50923; SUSHI; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Membrane {ECO:0000256|SAM:Phobius};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 901..924
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 330..389
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 391..502
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 505..566
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 568..679
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT DOMAIN 683..742
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 744..807
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 811..872
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..88
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..150
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..199
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 391..418
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00059"
FT DISULFID 713..740
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB26117.1"
FT NON_TER 960
FT /evidence="ECO:0000313|EMBL:EFB26117.1"
SQ SEQUENCE 960 AA; 103938 MW; 8BF6067762CAC851 CRC64;
GLSSEAPTTG EGQAPGIEEM DGELTVAPTP EQPERGVHFV TTAPTLKLLN HHPLLEEFLQ
EGPEGGEEGL RPALPFQPDP PTPFTPSPLP RLANQDSRPV FTSPTPAMAA APTQPQSRER
PWSLESESPV LRITTPLPPV PSPGPGEGPS TTPPSRAWTP TQEGPGDMGR PWAPEVRSRT
MGLGTEGTIT TSTASGDDEE TTTTIITTTI TTVQPPGPCS WNFSGPEGSL DSPTAPSSPT
DVGLDCFYYI SVYPGYGVEI KVQNISLREG ETVTVEGLGG PDPLPLANQS FLLRGQVIRS
PTHQAALRFQ SLPPPAGPGT FHFHYQAYLL NCHFPQRPAY GAVTVTSLHP GGSARFRCAT
GYQLKGARLL TCLNATQPFW DFQEPVCIAA CGGVTRNATT GRIVSPGFPG NYSSNLTCHW
LLEAPEGQRL HLHFEKVSLA EDDDRLIIRN GDNVEAPPVY DSYEVEYLPI EGLLSSGRHF
FVELSTDSSG AAAGMALRYE AFQQGHCYEP FVKYGNFSSS APSYPVGTTV EFSCDPGYTL
EQGSIIIECI DPHDPQWNET EPACRAVCSG EITDSAGVVL SPNWPEPYSR GQDCIWGVHV
EEDKRILLDI RVLRIGPGDV LTFYDGDDLT ARVLGQYSGP RGHFKLFTSM ADVTIQFQSD
PGASVLGYQQ GFVIHFFEVP RNDTCPELPE IPNGWKSPSQ PELVHGTVVT YQCYPGYQVV
GSSVLMCQWD LTWSEDLPSC QRVTSCHDPG DVEHSRRLIS NPKFPVRATV QYICDQGFVL
TGSAILTCHD RQASSPKWSD RTPKCLLEQL KPCHGLSAPE NGAHSPEKRL HPAGATVHFS
CAPGYVLKGQ ASIKCVPGHP SHWSDPPPIC RAASLDGFYS GRSLDVAKAP AASSTLDAAH
IAAAIFLPLV VMALLVGGVC LYFSRLQGKS PPLRLPRTRP RPYDRITVES AFDNPTYEIG
//
