ID D2GV14_AILME Unreviewed; 922 AA.
AC D2GV14;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=FCH and mu domain containing endocytic adaptor 1 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PANDA_000531 {ECO:0000313|EMBL:EFB19103.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB19103.1};
RN [1] {ECO:0000313|EMBL:EFB19103.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SUBCELLULAR LOCATION: Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004283}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004283}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004283}.
CC -!- SIMILARITY: Belongs to the FCHO family.
CC {ECO:0000256|ARBA:ARBA00011064}.
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DR EMBL; GL192348; EFB19103.1; -; Genomic_DNA.
DR AlphaFoldDB; D2GV14; -.
DR InParanoid; D2GV14; -.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR CDD; cd07674; F-BAR_FCHO1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR042735; FCHo1_F-BAR.
DR InterPro; IPR028565; MHD.
DR InterPro; IPR018808; Muniscin_C.
DR PANTHER; PTHR23065:SF6; F-BAR DOMAIN ONLY PROTEIN 1; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF10291; muHD; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077}.
FT DOMAIN 1..239
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 658..921
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
FT REGION 298..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 420..632
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..536
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..632
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB19103.1"
FT NON_TER 922
FT /evidence="ECO:0000313|EMBL:EFB19103.1"
SQ SEQUENCE 922 AA; 99995 MW; 384F4F0E1B15DD74 CRC64;
GEKNHGFEVL YHSVKQGPIS TKELADFIRE RATVEETYSK AMAKLSKLAS NGTPMGTFAP
LWEVFRVSSD KLALCHLELT RKLQDLIKDV LRYGEEQLKM HKKCKEEAVG TLDAVQVLAG
VSQLLPKSRE NYLNRCMDQE RLRRESTSQK EMDKAETKTK KAAESLRRSV EKYNSARADF
EQKMLDSALR FQAMEETHLR HMKALLGSYA HSVEDTHVQI GQVHEEFKQN IENVSVEMLL
RKFAESKGTG REKPGPLDFE AYSAAALQEG KAQLHPPHLF SAMKRLRGAK AFRLPGLSRR
EREPPAAVDS LEPDSGTCPE VDEEGFTVRP DVTQNNILLV PPGGNCLRAE LRETPMLGSA
WPLDCGARTA EPARFSSSDS DFDDEEPRKF YVHIKPAPAR APACSPEVAA AQLRATAGSL
ILPPAPGGTM KRHSARDAAG KPQRPRSAPR ASSCAEKLQS DEQFSKNLFG PPLESAFDHE
DFTGSSSLGF TSSPSPFSSS SPENVEDSGL DSPSHVAPGP SPDSWVPRPG TPQSPPSYRA
PASESRGTRP LPASDSPQPL APSPGPWGLE AVAGGDLMPG PADPAAREGL AAPPRRARAR
KVSCPLTRSN GDLSRSLSPS PLGSSTASTL SDRMGFSSQT AHGISRGPSP VVLGSQDALP
VATAFTEYVH AYFRGHGPSC LARVTGELTM TFPAGIVRVF SGTPPPPVLS FRLVHASAIE
HFQPNADLLF SDPSQSDPET KDFWLNMAAL TEALQRQAEQ NPAASYYNVV LLRYQFSRPG
PQSVPLQLSA HWQCGATLTQ VSVEYSYRPG ATAVPTPLTN VQILLPVREP VTNIRLQPAA
TWNLEEKRLL WKLPDVSEAG GSGHLSASWE PCSGSSTPSP VAAQFTSEGT TLSGVDLELV
GSGYRMSLVK RRFATGMYLV SC
//
