ID D2H6M9_AILME Unreviewed; 581 AA.
AC D2H6M9;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 24-JAN-2024, entry version 58.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
DE Flags: Fragment;
GN ORFNames=PANDA_005644 {ECO:0000313|EMBL:EFB21165.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB21165.1};
RN [1] {ECO:0000313|EMBL:EFB21165.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
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DR EMBL; GL192531; EFB21165.1; -; Genomic_DNA.
DR AlphaFoldDB; D2H6M9; -.
DR InParanoid; D2H6M9; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd01475; vWA_Matrilin; 1.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180}.
FT DOMAIN 12..191
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 364..539
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB21165.1"
FT NON_TER 581
FT /evidence="ECO:0000313|EMBL:EFB21165.1"
SQ SEQUENCE 581 AA; 63314 MW; 79A2163775FEFC92 CRC64;
LKGPRCRTGP LDLVFVIDSS RSVRPFEFET MRQFLVGLLR GLDVGPNATR VGVIQYSSQV
QSVFPLGAFA RREDMEHAIR ALVPLAQGTM TGLAIQYAMN VAFSVAEGAR PPEARVPRIA
VIVTDGRPQD RVAEVAAQAR ARGIEIYAVG VQRADVGSLR AMASPPLDEH VFLVESFDLI
QEFGLQFQGR LCGKDLCAEG GHGCQHQCVS APGTFHCACN PGYQLAADNK SCLAIDLCAE
GTHGCEHHCI SSPGSYFCRC QAGFVLQQDQ RSCRAIDHCS FGNHSCQHEC VSTFAGPRCY
CREGHDLLPD GRSCQARDLC NGVDHGCEFQ CVSEGHSYRC LCPEGQQLQA DGKSCNRCRE
GHVDLVLLVD GSKSVRPQNF ELVKRFVNQI VDFLDVSPEG TRVGLVQFSS RVRTEFPLGR
YGTAAEVKQA VLAVEYMERG TMTGLALRHM VEHSFSEAQG ARPRALNVPR VGLVFTDGRS
QDDISVWAAR AKEEGIVMYA VGVGKAVEEE LRQIASEPAE LHVSYSPDFG TMTHLLDNLR
GSICPEEGIG AGTELRSPCE CESLVEFQGR TLGALETLTQ N
//
