ID D2H6Q6_AILME Unreviewed; 965 AA.
AC D2H6Q6;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Sorting nexin 13 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PANDA_005679 {ECO:0000313|EMBL:EFB24785.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB24785.1};
RN [1] {ECO:0000313|EMBL:EFB24785.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL192533; EFB24785.1; -; Genomic_DNA.
DR AlphaFoldDB; D2H6Q6; -.
DR InParanoid; D2H6Q6; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06873; PX_SNX13; 1.
DR CDD; cd08719; RGS_SNX13; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037437; SNX13_PX.
DR InterPro; IPR037896; SNX13_RGS.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..281
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 370..493
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 567..688
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB24785.1"
FT NON_TER 965
FT /evidence="ECO:0000313|EMBL:EFB24785.1"
SQ SEQUENCE 965 AA; 111808 MW; 9FCC7F196C96B413 CRC64;
QTSLSIWGWG SLGIVLSLIT FGPFVIFYLA FYILCFVGGG FVVTLLFGKT NSEKYLEQCE
HSFLPPTSTG IPKCLEEMKR EARTIKIDRR LTGANIIDEP LQQVIQFSLR DYVQYWYYTL
SDDESFLLEI RQTLQNALIQ FATRSKEIDW QPYFTTRIVD DFGTHLRVFR KAQQKITEKD
DQAKGTAEDL VDTFFEVEVE MEKDVCRDLV CTSPKDEEGF LRDLCEVLLY LLLPPGDFQN
KIMRYFVREI LARGILLPLI NQLSDPDYIN QYIIWMIRDS NCNYEAFMNI IKLSDNIGEL
EAVRDKAAEE LQYLRSLDTV GDDINTIKNQ INSLLFVKKV CDSRIQRLQS GKEINTVKLA
ANFGKLCTVP LDSILVDNVA LQFFMDYMQQ TGGQAHLFFW MTVEGYRVTA QQQLEVLLSR
QKDGKHQTNQ TKGLLRAAAV GIYEQYLSEK ASPRVTVDDY LVAKLADTLN HEDPTPEIFD
DIQRKVYELM LRDERFYPSF RQNALYVRML AELDMLKDPS FRGSDDGDGE SFNGSPTGSI
NLSLDDLSNV SSDDSVQLHA YISDTVYADY DPYAVAGVCN DHGKTYALYA ITVHRRSLNS
EEMWKTYRRY SDFHDFHMRI TEQFENLSSI LKLPGKKTFN NMDRDFLEKR KKDLNAYLQL
LLTPEMMKAS PALAHYVYDF LENKAYSKGK GDFARKMDTF VNPLRNSMRN VSNAVKSLPD
SLAEGMTKMS DNMGKMSERL GQDIKQSFFK VPPLIPKTDS DPEHCRVSAQ LDDTVDDNIP
LRVMLLLMDE VFDLKERNQW LRRNIKNLLQ QLIRATYGDT INRKIVDHVD WMTSPEQVAD
LVKRFRDAFW PNGILAETVP CRDKAIRMRT RVAGKTKLLS IMPDELKHII GAETTRKGIL
RVFEMFQHNQ LNRRMVYVFL EGFLETLFPQ YKFRELFNKL HSRSKQIQKY KQKLQTTQAP
SLQKR
//
