ID D2H8T9_AILME Unreviewed; 1049 AA.
AC D2H8T9;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=StAR related lipid transfer domain containing 13 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=PANDA_006688 {ECO:0000313|EMBL:EFB24755.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB24755.1};
RN [1] {ECO:0000313|EMBL:EFB24755.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
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DR EMBL; GL192584; EFB24755.1; -; Genomic_DNA.
DR AlphaFoldDB; D2H8T9; -.
DR InParanoid; D2H8T9; -.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04375; RhoGAP_DLC1; 1.
DR CDD; cd08909; START_STARD13-like; 1.
DR Gene3D; 1.10.287.2070; -; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 6.10.250.1870; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR PANTHER; PTHR12659; RHO-TYPE GTPASE ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR12659:SF6; STAR-RELATED LIPID TRANSFER PROTEIN 13; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF01852; START; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00234; START; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50848; START; 1.
PE 4: Predicted;
FT DOMAIN 599..804
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 850..1018
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT REGION 85..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..147
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..284
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB24755.1"
FT NON_TER 1049
FT /evidence="ECO:0000313|EMBL:EFB24755.1"
SQ SEQUENCE 1049 AA; 117278 MW; C1A1B328A5AAA110 CRC64;
LFSDSQFPIN IVAVKNDHDF LEKDLVEPLY RRLNTLNKCA SMKLDVNFQR KKGDDSDEED
LCISNKWTFQ RTSRRWSRVD DLHTLFPGGD RNGSSGDIRM RNTTSSESVL TDLSEPEVCS
IHSESSGGSD SRSQPGSSHS TGRESFDCLG QSCPDSPVML DATFVSGGLP QSPKDVLSYP
LHPKNEKPTR ARAKSFLKRM ETLRGKGAHG RHKGPGRTGG LVISGPVLQQ EPEAFKAMHC
IPIPNGDLQS SPPTACTKGL LSASKWSRES SQSENSSSGV STPGLKERKC QEANKRGGMY
LEDLDVLAET ALRDAGNQNH THEFHSQENL VVHIPKDHKP GTFPKALSIE SLSPTDSSNG
VNWRTGSISL GRQQGPGARE PRLMASCHRA SRVSIYDNVP GSHLYASTGD LLDLEKDDLF
PHLDDILHHV NGLQEVVDGW SKNVLPELQT HDALVGEPGL CPFPSPNQIT LDFEGNSVSE
GRTTPSDVER DGTSLNESEA TGVRERRDSG VGASLTRPNR RLRWDSFQLS HQPQPSAAPH
ISNQTAGQLN LLQRFSLLRL TAVMEKYSMS NKHGWTWSVP KFMKRMKVPD YKDKTVFGVP
LIVHVQRTGQ PLPQSIQQAL RYLRSNCLDQ VGLFRKSGVK SRIHALRQMN ENFPENVSYE
DQSAYDVADM VKQFFRDLPE PLFTNKLSET FLHIYQYVPK EQRLQAVQAA ILLLADENRE
VLQTLLCFLN DVVNLVEENQ MTSMNLAVCL APSLFHLNLL KKESSPRVIQ KKYATGKPDQ
KDLSENLAAA QGLAHMITEC DRLFEVPHEL VAQSHNSYVE AEIHAPTLED LGTPLEESGA
TFHTYLEHLV RGLQKEAKEK FKGWVTCSST DNTDLAFKKV GDRHPLKLWK ASVEVEAPPS
VVLNRVLRER HLWDEDFVQW KVVETLDKQT EIYQYVLNSM APHPSRDFVV LRTWRTDLPK
GMCTLVSLSV EHEEAQLMGG VRAVVMDSQY LIEPCGSGKS RLTHICRIDL KGHSPEWYNK
GFGHLCAAEV ARIRNTFQPL IAEGPETKI
//
