ID D2HCT4_AILME Unreviewed; 414 AA.
AC D2HCT4;
DT 09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT 09-FEB-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
DE Flags: Fragment;
GN ORFNames=PANDA_008426 {ECO:0000313|EMBL:EFB29571.1};
OS Ailuropoda melanoleuca (Giant panda).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
OX NCBI_TaxID=9646 {ECO:0000313|EMBL:EFB29571.1};
RN [1] {ECO:0000313|EMBL:EFB29571.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20010809; DOI=10.1038/nature08696;
RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., Li B.,
RA Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., Jian M., Li J.,
RA Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., Ryder O.A.,
RA Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., Guo X., Wang B.,
RA Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., Wang G., Yu C., Nie W.,
RA Wang J., Wu Z., Liang H., Min J., Wu Q., Cheng S., Ruan J., Wang M.,
RA Shi Z., Wen M., Liu B., Ren X., Zheng H., Dong D., Cook K., Shan G.,
RA Zhang H., Kosiol C., Xie X., Lu Z., Zheng H., Li Y., Steiner C.C.,
RA Lam T.T., Lin S., Zhang Q., Li G., Tian J., Gong T., Liu H., Zhang D.,
RA Fang L., Ye C., Zhang J., Hu W., Xu A., Ren Y., Zhang G., Bruford M.W.,
RA Li Q., Ma L., Guo Y., An N., Hu Y., Zheng Y., Shi Y., Li Z., Liu Q.,
RA Chen Y., Zhao J., Qu N., Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X.,
RA Vinar T., Wang Y., Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y.,
RA Wang X., Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L.,
RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., Wang J.,
RA Wang J.;
RT "The sequence and de novo assembly of the giant panda genome.";
RL Nature 463:311-317(2010).
CC -!- SUBUNIT: Interacts with PTBP2; the interaction is direct.
CC {ECO:0000256|ARBA:ARBA00034798}.
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DR EMBL; GL192698; EFB29571.1; -; Genomic_DNA.
DR AlphaFoldDB; D2HCT4; -.
DR HOGENOM; CLU_022670_1_1_1; -.
DR InParanoid; D2HCT4; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22436; KH-I_NOVA_rpt2; 1.
DR CDD; cd09031; KH-I_NOVA_rpt3; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR InterPro; IPR047276; KH-I_NOVA_rpt2.
DR InterPro; IPR047274; KH-I_NOVA_rpt3.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF229; RNA-BINDING PROTEIN NOVA-1; 1.
DR Pfam; PF00013; KH_1; 2.
DR SMART; SM00322; KH; 2.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR PROSITE; PS50084; KH_TYPE_1; 2.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00117}.
FT DOMAIN 77..149
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 327..400
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 44..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFB29571.1"
FT NON_TER 414
FT /evidence="ECO:0000313|EMBL:EFB29571.1"
SQ SEQUENCE 414 AA; 41862 MW; 7D26AF4C5A066C1C CRC64;
GTTERVCLIQ GTVEALNAVH GFIAEKIREM PQNVAKTEPV SILQPQTTVN PDRIKQTLPS
SPTTTKSSPS DPMTTSRANQ VKIIVPNSTA GLIIGKGGAT VKAIMEQSGA WVQLSQKPDG
INLQERVVTV SGEPEQNRKA VELIIQKIQE DPQSGSCLNI SYANVTGPVA NSNPTGSPYA
NTAEVLPTAA AAAGLLGHAN LAGVAAFPAV LSGFTGNDLV AITSALNTLA SYGYNLNTLG
LGLSQAAATG ALAAAAASAN PAAAAANLLA TYASEASASG STAGGTAGTF ALGSLAAATA
ATNGYFGAAS PLAASAILGT EKSTDGSKDV VEIAVPENLV GAILGKGGKT LVEYQELTGA
RIQISKKGEF VPGTRNRKVT ITGTPAATQA AQYLITQRIT YEQGVRAANP QKVG
//
